Biotech Stocks Surge: Coherus Up 9.09% in After-Hours Trading
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jan 23 2026
0mins
Source: NASDAQ.COM
- Coherus Performance: Coherus Oncology, Inc. (CHRS) rose 9.09% in after-hours trading, closing at $1.73 with a $0.14 gain, indicating strong investor confidence in its future prospects.
- Sensei Biotech Surge: Sensei Biotherapeutics, Inc. (SNSE) surged 10.06% after hours, finishing at $12.47 with a $1.14 increase, reflecting positive market expectations for its products.
- uniQure Significant Jump: uniQure N.V. (QURE) posted a 9.96% rise in after-hours trading, closing at $24.95 with a $2.26 gain, suggesting investor optimism regarding its R&D progress.
- IO Biotech Strategic Exploration: Although IO Biotech, Inc. (IOBT) had no fresh news on Thursday, its stock still gained 4.19%, closing at $0.50, indicating market interest in its exploration of strategic alternatives, including potential mergers or asset sales.
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Analyst Views on CHRS
Wall Street analysts forecast CHRS stock price to rise
3 Analyst Rating
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 1.560
Low
4.00
Averages
5.50
High
7.00
Current: 1.560
Low
4.00
Averages
5.50
High
7.00
About CHRS
Coherus Oncology, Inc., formerly Coherus BioSciences, Inc., is a fully integrated commercial-stage oncology company with an approved PD-1 inhibitor, LOQTORZI, and a pipeline that includes two mid-stage clinical candidates targeting liver, lung, head & neck, and other cancers. LOQTORZI (toripalimab-tpzi) is its immuno-oncology franchise. LOQTORZI is the FDA-approved treatment indicated in combination with chemotherapy for recurrent or metastatic nasopharyngeal carcinoma (NPC) and is also in development for the treatment of additional tumor types. Its CHS-114 pipeline is a highly selective cytolytic CCR8 antibody that specifically binds and preferentially depletes CCR8+ tumor regulatory T cells (Tregs) with no off-target binding. Its Casdozokitug pipeline is a first-in-class, clinical-stage IL-27 antagonist, with demonstrated monotherapy activity in treatment-refractory NSCLC and clear cell renal cell carcinoma (ccRCC) and combination activity in hepatocellular carcinoma (HCC).
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Clinical Collaboration Agreement: Coherus Oncology and Zumutor Biologics have signed a clinical collaboration and supply agreement to study the novel anti-tumor monoclonal antibody ZM008 in conjunction with the PD-1 inhibitor LOQTORZI in a Phase 1 trial, aimed at evaluating its efficacy across various solid tumors.
- Patient Recruitment Plan: The study will enroll up to 45 patients, covering colorectal, head and neck, and non-small cell lung cancers, indicating potential therapeutic value for multiple hard-to-treat cancers and possibly providing new treatment options for patients.
- Safety and Tolerability Assessment: ZM008 has demonstrated a favorable safety profile in monotherapy studies, with no dose-limiting toxicities or anti-drug antibodies reported, and early clinical activity has been observed in metastatic patients previously treated with immune checkpoint inhibitors, suggesting its potential in
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- Clinical Collaboration Agreement: Coherus Oncology and Zumutor Biologics have signed a clinical collaboration and supply agreement to conduct a Phase 1 trial of ZM008 in combination with LOQTORZI, aiming to evaluate its efficacy across various solid tumors, marking a strategic expansion in the oncology immunotherapy field.
- Trial Design and Patient Recruitment: The trial plans to enroll up to 45 patients to assess the safety and tolerability of ZM008, particularly in hard-to-treat cancer patients, highlighting a strong demand for novel immunotherapy options and potentially laying the groundwork for future personalized treatments.
- Innovative Drug Potential: ZM008 has demonstrated favorable clinical outcomes in monotherapy, especially in metastatic patients previously unresponsive to immune checkpoint inhibitors, further validating its application potential in
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- LOQTORZI Revenue Projections: CEO Dennis Lanfear stated that LOQTORZI is projected to generate about $175 million annually in nasopharyngeal cancer, with expectations of reaching $15 million per quarter in 2026 and $30 to $35 million per quarter in 2027, indicating strong market potential.
- R&D Spending and Financing: CFO Bryan McMichael reported Q1 2026 R&D expenses of $21.5 million and total net proceeds of $54 million, providing financial backing for future clinical trials and market expansion efforts.
- Sales Dynamics and Market Performance: Despite Q1 LOQTORZI net sales of $11.8 million, a decline from the previous quarter, CCO Sameer Goregaoker highlighted record new patient starts, demonstrating sustained market demand.
- Future Outlook and Data Releases: Management anticipates quarterly demand growth of 10% to 15% throughout 2026 and plans to provide full-year 2026 revenue guidance during the August earnings call, further bolstering investor confidence.
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- Earnings Release Schedule: Coherus Oncology will release its Q1 2026 financial results after market close on May 11, which is expected to impact the company's future market performance.
- Management Conference Call: The management team will host a conference call at 5:00 p.m. ET on May 11 to discuss financial results and provide a business update, enhancing investor understanding of the company's strategy.
- Webcast Replay Availability: Investors can access a replay of the webcast on the company's website after the live call, ensuring transparency and compliance with regulatory requirements.
- Innovative Drug Pipeline: Coherus Oncology has a range of innovative oncology drugs, including the approved PD-1 inhibitor LOQTORZI®, and is advancing clinical candidates targeting various cancers, demonstrating the company's strategic positioning in cancer treatment.
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- Significant Revenue Growth: Coherus Oncology reported a net revenue of $40.8 million for 2025, a remarkable 113% increase from $19.1 million in 2024, indicating strong market acceptance of its next-gen PD-1 inhibitor, LOQTORZI, and suggesting enhanced future sales potential.
- Substantial Debt Reduction: The company successfully reduced its debt from $480 million to $38.8 million, a decrease of over 90%, significantly improving its financial position and providing greater funding flexibility for future R&D and market expansion.
- Increased R&D Spending: Despite overall cost control, Coherus raised its R&D expenses from $20.8 million to $31 million in Q4 2025, reflecting the company's commitment to new product development aimed at maintaining competitive advantage through innovation.
- Strong Cash Position: At the end of 2025, the company reported cash, cash equivalents, and investments totaling $172.1 million, ensuring financial stability for future operations and supporting potential strategic investments.
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