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CALC Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.090
Open
0.980
VWAP
0.99
Vol
452.71K
Mkt Cap
15.10M
Low
0.916
Amount
446.99K
EV/EBITDA(TTM)
--
Total Shares
15.80M
EV
14.14M
EV/OCF(TTM)
--
P/S(TTM)
--
CalciMedica, Inc. is a clinical-stage biopharmaceutical company. The Company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for inflammatory and immunologic diseases. The Company's technology targets the inhibition of CRAC channels to modulate the immune response and protect against tissue cell injury. Its lead product candidate is Auxora, a potent and selective intravenous formulated small molecule CRAC channel inhibitor containing the active compound zegocractin (formerly referred to as CM4620) that, in animal models, reduced acute epithelial and/or endothelial cell injury and inflammation in organs, such as the pancreas, lungs and kidneys. The Company is conducting a Phase IIb trial (called CARPO) for acute pancreatitis (AP) with systemic inflammatory response syndrome (SIRS), as well as supporting the ongoing Phase I/II asparaginase-induced pancreatic toxicity (AIPT) study (called CRSPA).
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Events Timeline

(ET)
2026-06-24
07:30:00
CalciMedica's KOURAGE Trial Receives FDA Review Approval
select
2026-06-24
07:30:00
CalciMedica Completes $49M Private Placement Financing
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2026-03-03 (ET)
2026-03-03
17:00:00
CalciMedica Files $125M Mixed Securities Shelf
select
2026-01-28 (ET)
2026-01-28
10:40:00
Calcimedica Inc Trading Halted Due to Volatility
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2026-01-28
07:10:00
CalciMedica Discontinues Phase 2 Clinical Trial of Auxora
select

News

NASDAQ.COM
5.0
06-29NASDAQ.COM
Adobe and CalciMedica Executives Increase Stock Holdings
  • Adobe Executive Purchase: On Thursday, Adobe's Director David A. Ricks purchased 10,000 shares of ADBE at $194.51 each, totaling $1.95 million, indicating strong confidence in the company's future performance, with a peak gain of 7.5% during the trading session.
  • Stock Price Fluctuation: On Monday, ADBE's stock reached a high of $209.13, reflecting a significant increase from Thursday's purchase price, contributing to a 2.9% rise in the stock on that day, showcasing positive market sentiment towards Adobe.
  • CalciMedica Purchase Details: Also on Thursday, Fred A. Middleton acquired 248,972 shares of CalciMedica at $0.80 each, totaling nearly $200,000, signaling optimism about the company's prospects, with CalciMedica's stock rising approximately 4% on Monday.
  • Market Reaction Analysis: The insider purchases by both executives not only reflect their confidence in the future growth of their respective companies but may also create a positive ripple effect among investors, increasing market interest and investment in both Adobe and CalciMedica.
PRnewswire
8.5
06-24PRnewswire
CalciMedica Secures $49 Million Financing to Advance Pulmonary Hypertension Strategy
  • Financing Details: CalciMedica has entered into a definitive securities purchase agreement for a private placement expected to raise approximately $49 million, primarily aimed at advancing its CRAC channel inhibition strategy for pulmonary arterial hypertension (PAH), with a Phase 1b study anticipated in mid-2027.
  • Clinical Trial Plans: The company intends to conduct a capital-efficient Phase 1b proof-of-concept study evaluating Auxora™, its intravenous CRAC channel inhibitor, in PAH patients, aiming to generate early human evidence for CRAC channel inhibition in pulmonary hypertension.
  • Market Potential and Strategic Importance: PAH represents a multi-billion-dollar market, and CalciMedica's CRAC channel inhibitors are positioned to potentially be the first therapy providing direct right ventricular support and anti-remodeling activity, addressing significant unmet needs in the market.
  • Safety and Development Outlook: Auxora has been evaluated in over 350 patients, demonstrating a favorable safety profile that supports its continued development across the pulmonary hypertension program and other indications, which is expected to provide robust support for the company's future clinical research.
PRnewswire
9.0
06-24PRnewswire
FDA Reviews CalciMedica's KOURAGE Trial Protocol Amendment
  • FDA Review Progress: The FDA has reviewed CalciMedica's protocol amendment and interim safety data for the KOURAGE trial without any comments, confirming the company's ability to continue dosing patients with Auxora in the study, thereby ensuring the continuity of clinical development.
  • Trial Enrollment Pause: In January 2026, CalciMedica paused enrollment in the KOURAGE trial due to safety concerns regarding mortality imbalance raised by the Independent Data Monitoring Committee, although no drug-related toxicity was identified, demonstrating the company's strong commitment to patient safety.
  • Protocol Amendment Details: The protocol amendment submitted by CalciMedica in March 2026 included refinements to patient inclusion criteria and changes to stratification methodology, aimed at addressing design issues and ensuring the scientific validity and efficacy of the trial.
  • Future Outlook: CalciMedica expects to receive feedback from the FDA in the third quarter of 2026 regarding the design of a potential pivotal program evaluating Auxora in acute pancreatitis, further advancing its clinical development plans.
Newsfilter
8.5
06-24Newsfilter
CalciMedica Secures $49 Million Financing for Pulmonary Hypertension Strategy
  • Financing Details: CalciMedica has entered into a definitive securities purchase agreement for a private placement expected to raise approximately $49 million, including $15 million in upfront proceeds, reflecting strong investor confidence in its pulmonary hypertension (PH) strategy.
  • Clinical Trial Plans: The company plans to conduct a Phase 1b proof-of-concept study for Auxora™ in mid-2027, aimed at providing early human evidence for CRAC channel inhibition in pulmonary arterial hypertension (PAH), thereby de-risking the development of CM5480.
  • Market Opportunity: PAH represents a multi-billion-dollar market, and CalciMedica's CRAC channel inhibitors are positioned to potentially be the first therapy to provide direct right ventricular support and anti-remodeling activity, addressing significant unmet medical needs in this area.
  • Safety Profile: Auxora has demonstrated a favorable safety profile in over 350 patients across clinical trials, supporting its continued development in the PH program and other indications, which is expected to bolster the company's future product pipeline.
Newsfilter
9.0
06-24Newsfilter
CalciMedica Receives FDA Review of KOURAGE Trial Progress
  • FDA Review Outcome: CalciMedica's KOURAGE trial for acute kidney injury has received FDA review with no comments, indicating that the company can continue dosing patients with Auxora in the study, ensuring the continuity of clinical development.
  • Trial Enrollment Pause: In January 2026, CalciMedica paused enrollment in the KOURAGE trial due to safety concerns raised by the Independent Data Monitoring Committee, although no drug-related toxicity was identified, necessitating a reevaluation of the study design to address imbalances in baseline disease severity among patients.
  • Protocol Amendment Submission: In March 2026, CalciMedica submitted a protocol amendment for the KOURAGE trial, refining patient inclusion criteria and changing stratification methods, ensuring a comprehensive safety assessment of 107 patients dosed prior to the enrollment pause, with no drug-related serious adverse events identified.
  • Future Outlook: CalciMedica expects to receive FDA feedback on the design of a potential pivotal program evaluating Auxora in acute pancreatitis in the third quarter of 2026, further advancing its clinical development plans.
seekingalpha
9.5
05-12seekingalpha
CalciMedica Reports Q1 2026 Financial Results with Significant Income Growth
  • Earnings Performance: CalciMedica reported a Q1 2026 GAAP EPS of -$0.30, indicating challenges in profitability that may affect investor confidence and market perception.
  • Cash Position: As of March 31, 2026, the company held $8.2 million in cash and cash equivalents, which is expected to sufficiently fund its operating plan into Q4 2026, reflecting a relatively stable liquidity management in the short term.
  • Significant Income Growth: Other income surged to $10.6 million in Q1 2026 from $1.5 million in Q1 2025, an increase of $9.1 million primarily due to fair value adjustments on promissory notes and common stock warrants, indicating improved asset management.
  • Financial Outlook: Despite the negative EPS, the substantial growth in cash flow and other income may lay the groundwork for future financial recovery, prompting investors to monitor the company's strategic adjustments and market responses closely.
Wall Street analysts forecast CALC stock price to rise
1 Analyst Rating
Wall Street analysts forecast CALC stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
20.00
Averages
20.00
High
20.00
Current: 0.000
sliders
Low
20.00
Averages
20.00
High
20.00
Oppenheimer
Oppenheimer
Outperform
downgrade
$20 -> $10
AI Analysis
2026-03-05
Reason
Oppenheimer
Oppenheimer
Price Target
$20 -> $10
AI Analysis
2026-03-05
downgrade
Outperform
Reason
Oppenheimer lowered the firm's price target on CalciMedica to $10 from $20 and keeps an Outperform rating on the shares. The firm notes CalciMedica reported updates to its programs in acute kidney injury and acute pancreatitis along with quarterly financials. The most important development is the absence of any drug-related toxicity following thorough internal/external review of the unblinded Phase 2 KOURAGE dataset - as CalciMedica had indicated after voluntarily discontinuing the trial in late January.
H.C. Wainwright
H.C. Wainwright
Buy -> Neutral
downgrade
2026-01-29
Reason
H.C. Wainwright
H.C. Wainwright
Price Target
2026-01-29
downgrade
Buy -> Neutral
Reason
H.C. Wainwright downgraded CalciMedica to Neutral from Buy without a price target. The immediate discontinuation for the Phase 2 KOURAGE clinical trial in acute kidney injury removes a major catalyst for the shares, the analyst tells investors in a research note. The firm looks to upcoming safety and population clarity as the company reviews the unblinded dataset to determine a potential path forward.
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Valuation Metrics

The current forward P/E ratio for CalciMedica Inc (CALC.O) is 0.00, compared to its 5-year average forward P/E of -1.87. For a more detailed relative valuation and DCF analysis to assess CalciMedica Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.87
Current PE
0.00
Overvalued PE
-0.93
Undervalued PE
-2.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.70
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.08
Undervalued EV/EBITDA
-1.32

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Frequently Asked Questions

What is CalciMedica Inc (CALC) stock price today?

The current price of CALC is 0.9559 USD — it has decreased -3.24

What is CalciMedica Inc (CALC)'s business?

CalciMedica, Inc. is a clinical-stage biopharmaceutical company. The Company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for inflammatory and immunologic diseases. The Company's technology targets the inhibition of CRAC channels to modulate the immune response and protect against tissue cell injury. Its lead product candidate is Auxora, a potent and selective intravenous formulated small molecule CRAC channel inhibitor containing the active compound zegocractin (formerly referred to as CM4620) that, in animal models, reduced acute epithelial and/or endothelial cell injury and inflammation in organs, such as the pancreas, lungs and kidneys. The Company is conducting a Phase IIb trial (called CARPO) for acute pancreatitis (AP) with systemic inflammatory response syndrome (SIRS), as well as supporting the ongoing Phase I/II asparaginase-induced pancreatic toxicity (AIPT) study (called CRSPA).

What is the price predicton of CALC Stock?

Wall Street analysts forecast CALC stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CALC is20.00 USD with a low forecast of 20.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is CalciMedica Inc (CALC)'s revenue for the last quarter?

CalciMedica Inc revenue for the last quarter amounts to -5.61M USD, decreased -13.64

What is CalciMedica Inc (CALC)'s earnings per share (EPS) for the last quarter?

CalciMedica Inc. EPS for the last quarter amounts to -4856000.00 USD, decreased -0.63

How many employees does CalciMedica Inc (CALC). have?

CalciMedica Inc (CALC) has 16 emplpoyees as of July 08 2026.

What is CalciMedica Inc (CALC) market cap?

Today CALC has the market capitalization of 15.10M USD.