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CRNX Overview

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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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0.000
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
83.631
Open
83.580
VWAP
83.53
Vol
80.92M
Mkt Cap
8.81B
Low
83.430
Amount
6.76B
EV/EBITDA(TTM)
--
Total Shares
105.44M
EV
3.16B
EV/OCF(TTM)
--
P/S(TTM)
225.17
Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity.
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Events Timeline

(ET)
2026-07-07
16:30:00
Nasdaq Retreats Amid Chip Sector Declines
select
2026-07-07
16:30:00
TD Cowen Downgrades Crinetics to Hold
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2026-07-07
13:00:00
Citizens Analyst Downgrades Crinetics to Market Perform After $85 Acquisition by Vertex Pharmaceuticals
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2026-07-07
12:30:00
Crinetics Stock Rises 98.8% to $83.55
select
2026-07-07
12:00:00
Nasdaq Index Falls Over 1% Amid Chip Sector Losses
select
2026-07-07
10:30:00
Crinetics Stock Rises 98.8% to $83.55
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2026-07-07
10:00:00
Wedbush: Vertex Acquires Crinetics for $85/Share
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News

PRnewswire
8.5
07-06PRnewswire
PinnedAdemi LLP Investigates Crinetics for Fiduciary Breaches
  • Shareholder Rights Investigation: Ademi LLP is investigating Crinetics for potential breaches of fiduciary duty in its transaction with Vertex, aiming to protect shareholder rights and ensure transparency in corporate governance.
  • Transaction Value Assessment: Crinetics shareholders are set to receive $85.00 per share, totaling approximately $10 billion in equity value, with a net value of $8.8 billion after estimated cash acquired, highlighting the substantial returns but raising concerns about the board's conduct.
  • Anti-competitive Clauses: The transaction agreement imposes unreasonable restrictions on competing bids, penalizing Crinetics significantly if it accepts alternative offers, which could harm shareholder interests and limit market competition, prompting legal scrutiny.
  • Board Accountability Review: We are examining whether Crinetics' board has fulfilled its fiduciary duties to all shareholders, ensuring that their decisions align with shareholder best interests and avoiding potential conflicts of interest and misconduct.
Fool
8.5
07-07Fool
Vertex Acquires Crinetics for $10 Billion to Expand Rare Disease Portfolio
  • Acquisition of Crinetics: Vertex Pharmaceuticals is acquiring Crinetics Pharmaceuticals for $10 billion, aiming to expand its business into endocrine diseases, with the potential to add up to $5 billion in annual revenue over the long term, although the market reacted negatively in the short term, pushing the stock down about 2%.
  • Strategic Fit: Vertex CEO Reshma Kewalramani praised the acquisition as an excellent strategic fit, as Crinetics focuses on serious diseases in specialty markets with significant unmet needs, and it is expected to contribute revenue immediately through the ongoing launch of the Palsonify medicine.
  • Revenue Growth Potential: The growing demand for therapeutics in endocrine diseases provides Vertex with a clear runway for double-digit revenue growth in the coming years, with Crinetics in the portfolio further solidifying its market position.
  • Strong Market Performance: Since February 2022, Vertex's stock has outperformed the S&P 500 by 45%, demonstrating strong investor appeal, particularly in the current market environment.
NASDAQ.COM
6.5
07-07NASDAQ.COM
Analyst Target Price vs ETF Performance Analysis
  • ETF Potential Analysis: The iShares US Pharmaceuticals ETF (IHE) has an implied analyst target price of $109.89 per unit, while trading at $100.19, indicating a 9.68% upside, reflecting market optimism about the ETF's future performance.
  • Outstanding Stock Performance: Crinetics Pharmaceuticals (CRNX) trades at $42.03, with an analyst target price of $83.14, suggesting a potential upside of 97.82%, showcasing strong market confidence in its future growth.
  • Optimistic Industry Outlook: CorMedix (CRMD) is priced at $8.79, with a target price of $14.00, indicating a 59.27% upside, reflecting analysts' positive expectations regarding its products and market demand.
  • Zoetis Growth Potential: Zoetis (ZTS) trades at $75.42, with an analyst target price of $114.12, showing a 51.32% upside, indicating analysts' optimism about its continued growth in the animal health sector.
CNBC
2.0
07-07CNBC
Fiserv Discusses Sale of Payments Business with Major Banks
  • Stock Surge: Fiserv shares rallied over 5% after The Wall Street Journal reported discussions with major banks like JPMorgan and Bank of America regarding the sale of its payments infrastructure business, potentially leading to strategic restructuring and enhanced market competitiveness.
  • Acquisition Deal: Vertex Pharmaceuticals announced a $10 billion acquisition of Crinetics Pharmaceuticals to expand its product line in rare hormonal disease treatments, although Vertex shares dipped nearly 1%, this deal is expected to strengthen its market position.
  • Stock Upgrade: First Solar's stock rose nearly 3% after Deutsche Bank upgraded its rating from neutral to buy, with analysts citing potential trade policy shifts as a reason for investors to buy the dip, boosting market confidence.
  • EV Stock Decline: Rivian shares tumbled 9% despite revenue and delivery guidance exceeding market expectations, as the company announced a plan to sell 75 million new shares for a significant capital raise, negatively impacting investor sentiment.
seekingalpha
8.5
07-07seekingalpha
Crinetics Pharmaceuticals Doubles After Vertex Acquisition Deal
  • Acquisition Surge: Crinetics Pharmaceuticals' shares doubled to $85 per share after Vertex Pharmaceuticals agreed to acquire the company in an all-cash deal valued at approximately $10 billion, with the transaction expected to close in Q3 2026, which will immediately boost Vertex's revenue, particularly through the launch of Palsonify for acromegaly.
  • Potential Revenue Opportunities: Vertex anticipates that the combined assets will generate over $5 billion in peak annual revenue, especially with its pipeline candidate atumelnant potentially becoming a multi-billion-dollar market opportunity, highlighting the strategic significance of the acquisition.
  • Divergent Market Reactions: While Crinetics' stock surged, Rivian Automotive's shares fell by 9% due to the announcement of a 75 million share Class A stock offering, overshadowing its stronger-than-expected Q2 revenue guidance, indicating investor caution towards electric vehicle manufacturers.
  • Growing Industry Concerns: Micron Technology's shares dropped by 5% as investor worries about Samsung Electronics and SK Hynix's capital spending plans potentially leading to a memory supply glut intensified, further impacting the performance of the entire memory semiconductor sector.
stocktwits
8.5
07-07stocktwits
Sellas Life Sciences Stock Gains Retail Trader Favor Amid Bullish Sentiment
  • Retail Trader Enthusiasm: In a poll of 3,400 users, Sellas Life Sciences (SLS) garnered 50% of the votes, significantly outpacing Ondas Holdings at 24% and ImmunityBio at 18%, indicating strong investor confidence in its future potential.
  • Clinical Trial Progress: Sellas' Phase 3 Regal trial in acute myeloid leukemia (AML) has reached 78 of the 80 events needed for final analysis, making the next two events critical catalysts that could drive stock price volatility.
  • Acquisition Speculation: CEO Angelos Stergiou's optimistic remarks on social media and gratitude towards strategic partners have intensified market speculation regarding potential buyouts, likely attracting more investor interest.
  • Significant Market Value Increase: Sellas' market value surged from $73 million at the start of 2024 to over $1.5 billion by mid-2026, reflecting heightened investor attention around the Regal readout, while the company ended Q1 with $107.1 million in cash, showcasing a robust financial position.
Wall Street analysts forecast CRNX stock price to rise
11 Analyst Rating
Wall Street analysts forecast CRNX stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
67.00
Averages
89.40
High
105.00
Current: 0.000
sliders
Low
67.00
Averages
89.40
High
105.00
Jefferies
Buy
to
Hold
downgrade
$55 -> $85
AI Analysis
2026-07-07
New
Reason
Jefferies
Price Target
$55 -> $85
AI Analysis
2026-07-07
New
downgrade
Buy
to
Hold
Reason
Jefferies downgraded Crinetics (CRNX) to Hold from Buy with a price target of $85, up from $55, after the company announced it will be acquired by Vertex Pharmaceuticals (VRTX) for $85 per share. The firm, which calls the deal "a solid outcome" for Crinetics, sees limited FTC risk given minimal overlap between Vertex's portfolio and Crinetics' rare endocrinology franchise.
JonesResearch
JonesResearch
Buy
to
Hold
downgrade
$85
2026-07-07
New
Reason
JonesResearch
JonesResearch
Price Target
$85
2026-07-07
New
downgrade
Buy
to
Hold
Reason
JonesResearch downgraded Crinetics (CRNX) to Hold from Buy with an $85 price target after Vertex Pharmaceuticals (VRTX) agreed to acquire the company for $85 per share in cash.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CRNX
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Valuation Metrics

The current forward P/E ratio for Crinetics Pharmaceuticals Inc (CRNX.O) is 0.00, compared to its 5-year average forward P/E of -8.33. For a more detailed relative valuation and DCF analysis to assess Crinetics Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-8.33
Current PE
0.00
Overvalued PE
-5.43
Undervalued PE
-11.24

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-5.20
Current EV/EBITDA
-1.94
Overvalued EV/EBITDA
-1.96
Undervalued EV/EBITDA
-8.44

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
942.57
Current PS
25.73
Overvalued PS
2193.24
Undervalued PS
-308.09

Financials

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Quarterly

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Whales Holding CRNX

P
Paradigm Biocapital Advisors LP
Holding
CRNX
+33.08%
3M Return
D
Driehaus Capital Management LLC
Holding
CRNX
+21.50%
3M Return
F
Farallon Capital Management, L.L.C.
Holding
CRNX
+20.95%
3M Return
E
EcoR1 Capital, LLC
Holding
CRNX
+20.86%
3M Return
O
OrbiMed Advisors LLC
Holding
CRNX
+10.54%
3M Return
A
ADAR1 Capital Management, LLC
Holding
CRNX
+4.60%
3M Return

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Frequently Asked Questions

What is Crinetics Pharmaceuticals Inc (CRNX) stock price today?

The current price of CRNX is 83.53 USD — it has increased 98.74

What is Crinetics Pharmaceuticals Inc (CRNX)'s business?

Crinetics Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of therapeutics for rare endocrine diseases and endocrine-related tumors. Its lead development candidate, PALSONIFY (paltusotine), is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for acromegaly and carcinoid syndrome associated with neuroendocrine tumors. Its second product candidate is Atumelnant, which is in clinical development for congenital adrenal hyperplasia (CAH) and patients with either Cushing's disease or Ectopic ACTH Syndrome (EAS). Its drug candidates are orally delivered, small molecule new chemical entities resulting from in-house drug discovery efforts, including other programs addressing a variety of endocrine conditions such as hyperparathyroidism, polycystic kidney disease, Graves' disease, thyroid eye disease, diabetes and obesity.

What is the price predicton of CRNX Stock?

Wall Street analysts forecast CRNX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRNX is89.40 USD with a low forecast of 67.00 USD and a high forecast of 105.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Crinetics Pharmaceuticals Inc (CRNX)'s revenue for the last quarter?

Crinetics Pharmaceuticals Inc revenue for the last quarter amounts to 10.73M USD, increased 2873.41

What is Crinetics Pharmaceuticals Inc (CRNX)'s earnings per share (EPS) for the last quarter?

Crinetics Pharmaceuticals Inc. EPS for the last quarter amounts to -1.23 USD, increased 18.27

How many employees does Crinetics Pharmaceuticals Inc (CRNX). have?

Crinetics Pharmaceuticals Inc (CRNX) has 594 emplpoyees as of July 08 2026.

What is Crinetics Pharmaceuticals Inc (CRNX) market cap?

Today CRNX has the market capitalization of 8.81B USD.