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CRSP Overview

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0.000(0.000%)Aft-market
ET
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ET
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Intellectia

Loading chart...

High
62.800
Open
62.445
VWAP
60.72
Vol
1.67M
Mkt Cap
5.98B
Low
58.580
Amount
101.29M
EV/EBITDA(TTM)
--
Total Shares
98.48M
EV
4.11B
EV/OCF(TTM)
--
P/S(TTM)
1.39K
CRISPR Therapeutics AG is a Switzerland-based gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) and is a technology for gene editing, the process of precisely altering specific sequences of genomic DNA. The Company aims to apply this technology to disrupt, delete, correct and insert genes to treat genetically-defined diseases and to engineer advanced cellular therapies. The Company has acquired the rights to the intellectual property (IP) encompassing CRISPR/Cas9 and related technologies and is also involved in its own IP research and additional in-licensing efforts. The Company product development and partnership strategies are designed to exploit the full potential of the CRISPR/Cas9 platform while maximizing the probability of successfully developing their product candidates.
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Events Timeline

(ET)
2026-06-11
14:30:00
Jeff Bezos' New AI Venture Prometheus Raises $12B, Valuation Reaches $41B
select
2026-06-02 (ET)
2026-06-02
09:50:00
FDA Issues Draft Guidance for Gene Therapies
select
link
2026-05-12 (ET)
2026-05-12
14:00:00
FDA Commissioner Makary Resigns Over E-Cigarette Concerns
select
link
2026-05-04 (ET)
2026-05-04
16:50:00
CRISPR Therapeutics Reports Q1 Revenue of $1.4M
select

News

Fool
5.0
07-06Fool
Comparative Investment in Gene Editing and Metabolic Medicine
  • CRISPR's Market Position: CRISPR Therapeutics leads in gene editing, recently achieving its first product approval for rare blood disorders, yet its fiscal 2025 revenue of $3.5 million reflects a nearly 90% decline from the previous year, highlighting risks associated with its reliance on partnership-driven revenue.
  • Viking's Clinical Challenges: Viking Therapeutics focuses on therapies for metabolic and endocrine disorders, reporting no revenue in fiscal 2025 and a net loss of approximately $359.6 million, indicating high risks associated with its clinical pipeline investments and dependence on Ligand Pharmaceuticals' licensing agreement, which could jeopardize drug development.
  • Financial Health Comparison: CRISPR's current ratio stands at 13.3, indicating strong short-term solvency, but its free cash flow of negative $345.9 million underscores ongoing financial losses; conversely, Viking's current ratio of 9.3 and zero debt suggest a healthier financial structure, albeit with significant operational losses.
  • Investment Outlook Assessment: While CRISPR's high valuation with a forward P/E of 19.1 contrasts with Viking's 17.7, both companies exhibit substantial growth potential in the biotech market, yet CRISPR's minimal sales, despite being small, render it more appealing to investors compared to Viking's pre-revenue status.
NASDAQ.COM
8.5
07-06NASDAQ.COM
Investment Outlook for CRISPR and Viking Therapeutics
  • CRISPR Financial Challenges: CRISPR Therapeutics reported approximately $3.5 million in revenue for fiscal 2025, a nearly 90% decline year-over-year, with a net loss of about $581.6 million, highlighting the volatility of biotech revenues and increasing financial sustainability risks due to reliance on its partnership with Vertex Pharmaceuticals.
  • Viking Clinical Investments: Viking Therapeutics reported no revenue for fiscal 2025, with a net loss of approximately $359.6 million as it heavily invests in its clinical pipeline for obesity and metabolic diseases; despite its zero-debt financial status, it faces uncertainties regarding regulatory approvals.
  • Market Competition Analysis: CRISPR leads in gene editing with a high valuation but has achieved a breakthrough treatment for sickle cell disease, while Viking remains in the clinical stage without revenue, presenting higher investment risks.
  • Investor Considerations: While both companies operate in high-growth sectors, CRISPR's sales performance makes it more attractive to investors, whereas Viking's prospects depend on its licensing agreement with Ligand Pharmaceuticals, where any changes could significantly impact its drug development timeline.
stocktwits
8.5
07-02stocktwits
FDA Expands Approval for Casgevy Gene Therapy to Younger Patients
  • Expanded Indication: The FDA's approval of Casgevy now allows its use in children as young as two years old, significantly increasing the eligibility of approximately 5,500 additional children in the U.S., marking the first application of this therapy in the pediatric population and expected to greatly enhance Crispr's market potential.
  • Increased Commercial Opportunity: Crispr benefits from a 40% share of net profits from Casgevy under its collaboration with Vertex, and this expansion directly increases the potential revenue pool for Crispr, strengthening its competitive position in the gene therapy market.
  • Positive Market Reaction: Following the FDA approval, Crispr's stock surged 8%, reflecting investor optimism about the company's future growth, while Vertex's shares also rose 6%, indicating market recognition of its product line expansion.
  • Investor Sentiment Shift: On Stocktwits, retail sentiment around Crispr shifted from 'neutral' to 'bullish', with message volume significantly increasing, suggesting growing confidence in Crispr's future performance, which may drive further stock price appreciation.
NASDAQ.COM
4.5
07-02NASDAQ.COM
Analysis of ARKK ETF's 52-Week Price Fluctuations
  • Price Range Analysis: The ARKK ETF has a 52-week low of $62.945 and a high of $92.65, with the last trade at $82.55, indicating significant volatility and shifts in investor sentiment within the market.
  • Technical Analysis Tool: Comparing the current share price to the 200-day moving average provides investors with valuable insights for technical analysis, aiding in the assessment of market trends and potential buy or sell opportunities.
  • ETF Unit Trading Mechanism: Exchange-traded funds (ETFs) trade similarly to stocks, where investors buy and sell 'units' that can be created or destroyed based on investor demand, impacting the liquidity and market performance of the fund.
  • Inflows and Outflows Monitoring: Weekly monitoring of changes in shares outstanding for ETFs helps identify those experiencing notable inflows or outflows, as these liquidity shifts can significantly affect the performance of the underlying stocks held within the ETFs.
Fool
6.5
06-27Fool
Investment Comparison Between CRISPR and Vertex
  • CRISPR's Financial Challenges: CRISPR Therapeutics AG reported revenue of only $3.5 million for FY 2025, a staggering 90% decline year-over-year, reflecting significant challenges in its commercialization process, with a net loss of approximately $581.6 million indicating heavy investment needs for its clinical pipeline.
  • Vertex's Profitability: Vertex Pharmaceuticals generated nearly $12 billion in revenue for FY 2025, an 8.9% year-over-year increase, with a net income of about $4 billion and a net margin of 32.7%, showcasing its mature business model and stable cash inflows.
  • Risk Comparison: CRISPR faces substantial financial sustainability risks, including frequent capital raises and intellectual property litigation, while Vertex relies heavily on sales from its cystic fibrosis drugs, making it vulnerable to new competition and regulatory risks.
  • Valuation Differences: CRISPR has a forward P/E ratio of 18.6x but an astronomical P/S ratio of 1270x, whereas Vertex's forward P/E is 25.3x with a P/S ratio of 10x, highlighting significant differences in market valuations between the two companies.
NASDAQ.COM
8.5
06-27NASDAQ.COM
Investment Comparison: CRISPR vs. Vertex Pharmaceuticals
  • CRISPR Financial Struggles: CRISPR Therapeutics AG reported nearly $3.5 million in revenue for FY 2025, a staggering 90% decline year-over-year, primarily due to transitions in milestone recognition and commercial rollout, resulting in a net loss of approximately $581.6 million, highlighting the heavy investment burden on its clinical pipeline.
  • Vertex Profitability: Vertex Pharmaceuticals generated close to $12 billion in revenue for FY 2025, reflecting an 8.9% year-over-year increase, with a net income of approximately $4.0 billion and a net margin of 32.7%, indicating a mature business model with steady cash inflows.
  • Partnership Risks and Patent Litigation: CRISPR faces significant risks in its partnership with Vertex, including a patent infringement lawsuit from ToolGen, and any disruption in this relationship could materially harm its commercial prospects and long-term viability.
  • Divergent Investor Mindsets: Investors must weigh their risk tolerance when choosing between CRISPR and Vertex, as CRISPR represents a high-risk, high-reward gene-editing technology, while Vertex offers a stable cash-generating business suitable for those seeking patient investments.
Wall Street analysts forecast CRSP stock price to rise
10 Analyst Rating
Wall Street analysts forecast CRSP stock price to rise
8 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
50.00
Averages
78.89
High
105.00
Current: 0.000
sliders
Low
50.00
Averages
78.89
High
105.00
Morgan Stanley
Underweight
to
Equal Weight
upgrade
$33 -> $60
AI Analysis
2026-06-11
Reason
Morgan Stanley
Price Target
$33 -> $60
AI Analysis
2026-06-11
upgrade
Underweight
to
Equal Weight
Reason
Morgan Stanley upgraded Crispr Therapeutics to Equal Weight from Underweight with a price target of $60, up from $33, as the analyst assumed coverage. The firm looks for improved visibility on the Casgevy launch and pipeline value to emerge, adding that it sees a potential for inflection with greater visibility to revenue recognition and gentler conditioning and sees the in vivo delivery pipeline as in focus.
Bernstein
Market Perform
maintain
$50 -> $56
2026-05-13
Reason
Bernstein
Price Target
$50 -> $56
2026-05-13
maintain
Market Perform
Reason
Bernstein raised the firm's price target on Crispr Therapeutics to $56 from $50 and keeps a Market Perform rating on the shares. Biotech has had a strong start to 2026, up 11% year-to-date, outperforming Pharma and the S&P. The firm's coverage is up 7% year-to-date on a simple-average basis, and down 3% cap weighted - smaller names have outperformed. Overall, Bernstein maintains a positive view on the sector, as it expects M&A and IPO activity to remain healthy, and it views recent changes to FDA leadership as a tailwind, particularly for less mature companies.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CRSP
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Valuation Metrics

The current forward P/E ratio for CRISPR Therapeutics AG (CRSP.O) is 25.00, compared to its 5-year average forward P/E of -6.50. For a more detailed relative valuation and DCF analysis to assess CRISPR Therapeutics AG's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.50
Current PE
25.00
Overvalued PE
4.48
Undervalued PE
-17.49

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-8.31
Current EV/EBITDA
-0.49
Overvalued EV/EBITDA
4.09
Undervalued EV/EBITDA
-20.71

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
228.46
Current PS
40.78
Overvalued PS
556.10
Undervalued PS
-99.19

Financials

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Whales Holding CRSP

A
ARK Investment Management LLC
Holding
CRSP
+22.89%
3M Return
E
EcoR1 Capital, LLC
Holding
CRSP
+20.86%
3M Return
V
Vestmark Advisory Solutions, Inc.
Holding
CRSP
+8.18%
3M Return
C
Contrarius Investment Management Ltd.
Holding
CRSP
+7.77%
3M Return

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Frequently Asked Questions

What is CRISPR Therapeutics AG (CRSP) stock price today?

The current price of CRSP is 60.77 USD — it has decreased -1.81

What is CRISPR Therapeutics AG (CRSP)'s business?

CRISPR Therapeutics AG is a Switzerland-based gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) and is a technology for gene editing, the process of precisely altering specific sequences of genomic DNA. The Company aims to apply this technology to disrupt, delete, correct and insert genes to treat genetically-defined diseases and to engineer advanced cellular therapies. The Company has acquired the rights to the intellectual property (IP) encompassing CRISPR/Cas9 and related technologies and is also involved in its own IP research and additional in-licensing efforts. The Company product development and partnership strategies are designed to exploit the full potential of the CRISPR/Cas9 platform while maximizing the probability of successfully developing their product candidates.

What is the price predicton of CRSP Stock?

Wall Street analysts forecast CRSP stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CRSP is78.89 USD with a low forecast of 50.00 USD and a high forecast of 105.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is CRISPR Therapeutics AG (CRSP)'s revenue for the last quarter?

CRISPR Therapeutics AG revenue for the last quarter amounts to 1.46M USD, increased 68.55

What is CRISPR Therapeutics AG (CRSP)'s earnings per share (EPS) for the last quarter?

CRISPR Therapeutics AG. EPS for the last quarter amounts to -1.28 USD, decreased -18.99

How many employees does CRISPR Therapeutics AG (CRSP). have?

CRISPR Therapeutics AG (CRSP) has 393 emplpoyees as of July 08 2026.

What is CRISPR Therapeutics AG (CRSP) market cap?

Today CRSP has the market capitalization of 5.98B USD.