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CTMX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
3.890
Open
3.860
VWAP
3.80
Vol
3.19M
Mkt Cap
835.98M
Low
3.685
Amount
12.16M
EV/EBITDA(TTM)
--
Total Shares
217.70M
EV
482.74M
EV/OCF(TTM)
--
P/S(TTM)
17.18
CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors.
Show More

Events Timeline

(ET)
2026-06-03
08:10:00
CytomX Expands Collaboration Agreement with Regeneron
select
2026-05-07 (ET)
2026-05-07
18:20:00
CytomX Reports Q1 Revenue of $10.26M
select

News

PRnewswire
8.5
07-06PRnewswire
GT Biopharma Integrates AI to Accelerate Drug Development
  • AI Integration: GT Biopharma has integrated AI tools into the discovery and engineering of its tumor-targeting NK cell engagers and multi-domain proteins, with expectations to push multiple new development candidates into pre-IND development by 2027, thereby accelerating clinical timelines and reducing costs.
  • Drug Design Optimization: Utilizing AI-guided sequence and structural analyses, GT Biopharma can prioritize candidates with favorable binding, stability, and developability profiles, aiming to eliminate potential failures early in the discovery phase, thus minimizing costly fixes later in development.
  • Clinical Trial Progress: Currently, GT Biopharma's lead program GTB-3650 is in a Phase 1 trial for CD33-expressing blood cancers, while its second candidate GTB-5550 began dosing for B7-H3-expressing solid tumors in May 2026, indicating positive momentum in clinical development.
  • Future Development Potential: GT Biopharma plans to leverage its AI-enabled discovery engine to replenish its pipeline behind existing projects, targeting multiple new candidates for clinical development by 2027, thereby enhancing its competitive position in the rapidly evolving biopharmaceutical market.
NASDAQ.COM
5.0
07-01NASDAQ.COM
Rigel Pharmaceuticals Appoints New Chief Medical Officer
  • Executive Appointment: Rigel Pharmaceuticals has appointed Alison Hannah as Executive Vice President and Chief Medical Officer, succeeding Lisa Rojkjaer, which is expected to drive the company's strategic development in the biotechnology sector.
  • Board Changes: Hannah's appointment comes with her resignation from Rigel's Board of Directors, effective July 1, 2026, indicating a significant shift in the company's upper management.
  • Extensive Experience: Hannah previously served as Chief Medical Officer at CytomX Therapeutics, overseeing the clinical development of conditionally activated protein therapeutics, showcasing her strong background in the biopharmaceutical field.
  • Market Performance: Rigel's stock has traded between $18.24 and $52.24 over the past year, with the current price down 0.73% to $38.84, reflecting a cautious market sentiment regarding the new appointment.
NASDAQ.COM
7.5
06-04NASDAQ.COM
CytomX Expands Collaboration with Regeneron, Validating PROBODY Platform
  • Strategic Collaboration Expansion: CytomX Therapeutics has broadened its partnership with Regeneron Pharmaceuticals, securing $37 million upfront and potential milestone payments up to $4 billion, indicating strong market confidence in its PROBODY platform.
  • Clinical Development Progress: CytomX's Varseta-m is undergoing dose optimization with 40 patients enrolled, with data expected in the second half of 2026 to support a registrational study start in the first half of 2027, showcasing its potential in tumor treatment.
  • Combination Study Plans: Ongoing trials pairing Varseta-m with bevacizumab are anticipated to yield initial data in the first half of 2027, alongside a planned Phase 1/2 study combining multiple drugs in the second half of 2026, further expanding treatment indications.
  • Analyst Rating Upgrade: Wedbush analyst Robert Driscoll reaffirmed an Outperform rating on CTMX with a 12-month price target of $11.00, nearly triple the current share price, reflecting optimistic market expectations for CytomX's future growth.
seekingalpha
7.5
06-03seekingalpha
CytomX Expands Collaboration with Regeneron Worth Up to $4B
  • Collaboration Expansion: CytomX Therapeutics has expanded its collaboration with Regeneron Pharmaceuticals to a potential value of up to $4 billion, highlighting the depth of their partnership in cancer therapeutics.
  • Funding Injection: CytomX will receive $37 million for nominating two additional targets selected by Regeneron for clinical development, which not only enhances its liquidity but also supports subsequent research efforts.
  • Target Selection Opportunity: Regeneron will have the option to select up to six additional targets, a flexibility that could accelerate the development of new therapies, thereby enhancing CytomX's competitive position in the market.
  • Potential Revenue: The expanded agreement includes payments linked to target nomination, clinical, and commercial milestones, and CytomX will also be eligible for tiered royalties based on global net sales, further strengthening its long-term profitability.
NASDAQ.COM
2.0
06-02NASDAQ.COM
CytomX (CTMX) Q4 2025 Earnings Transcript
seekingalpha
9.5
05-08seekingalpha
CytomX Therapeutics Q1 2026 Earnings Call Insights
  • Significant Clinical Progress: CytomX's Q1 2026 earnings call highlighted excellent clinical progress with Varseta-M in late-line colorectal cancer, aiming for its inclusion in standard care, with a projected registrational study start in the first half of 2027, reflecting the company's strategic ambition in oncology.
  • Strong Patient Recruitment: As of now, CytomX has completed enrollment of 40 patients in dose optimization cohorts, with a total of 113 patients enrolled, and expects to provide an overall Phase I data update in the second half of this year, which will be crucial for future FDA interactions.
  • Robust Financial Position: CytomX ended Q1 2026 with $346.7 million in cash and equivalents, a significant increase from $137.1 million as of December 31, 2025, demonstrating financial stability post-financing, which supports future R&D initiatives.
  • Risk Management Strategies: Management emphasized that diarrhea is the principal adverse event of Varseta-M, and through updated patient management strategies, they expect to substantially reduce the incidence of high-grade diarrhea, indicating proactive risk mitigation efforts.
Wall Street analysts forecast CTMX stock price to rise
7 Analyst Rating
Wall Street analysts forecast CTMX stock price to rise
6 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
6.00
Averages
9.00
High
10.00
Current: 0.000
sliders
Low
6.00
Averages
9.00
High
10.00
Wolfe Research
Outperform
initiated
$6
AI Analysis
2026-05-19
Reason
Wolfe Research
Price Target
$6
AI Analysis
2026-05-19
initiated
Outperform
Reason
Wolfe Research initiated coverage of CytomX Therapeutics with an Outperform rating and $6 price target. The company owns the only \"de-risked\" epithelial cell adhesion molecule antibody-drug conjugate in clinical development, the analyst tells investors in a research note. The firm says that while toxicity is the concern, CytomX should be able to navigate this and drive acceptable Grade 3 rates. Wolfe views the recent pullback in the shares as a buying opportunity.
H.C. Wainwright
Buy
downgrade
$17 -> $11
2026-05-11
Reason
H.C. Wainwright
Price Target
$17 -> $11
2026-05-11
downgrade
Buy
Reason
H.C. Wainwright lowered the firm's price target on CytomX Therapeutics to $11 from $17 and keeps a Buy rating on the shares. The firm cites the company's financing-related dilution for the target cut.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for CTMX
Unlock Now

Valuation Metrics

The current forward P/E ratio for CytomX Therapeutics Inc (CTMX.O) is 14.20, compared to its 5-year average forward P/E of 14.73. For a more detailed relative valuation and DCF analysis to assess CytomX Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
14.73
Current PE
14.20
Overvalued PE
85.14
Undervalued PE
-55.69

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-12.96
Current EV/EBITDA
-12.43
Overvalued EV/EBITDA
41.50
Undervalued EV/EBITDA
-67.42

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
7.25
Current PS
24.21
Overvalued PS
19.90
Undervalued PS
-5.41

Financials

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Whales Holding CTMX

V
VR Management, LLC
Holding
CTMX
+31.72%
3M Return
C
Commodore Capital LP
Holding
CTMX
+22.07%
3M Return
K
Kynam Capital Management, LP
Holding
CTMX
+12.11%
3M Return
E
Eversept Partners, L.P.
Holding
CTMX
+11.03%
3M Return
A
ADAR1 Capital Management, LLC
Holding
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+4.60%
3M Return

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Frequently Asked Questions

What is CytomX Therapeutics Inc (CTMX) stock price today?

The current price of CTMX is 3.84 USD — it has increased 0.79

What is CytomX Therapeutics Inc (CTMX)'s business?

CytomX Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company. The Company is focused on developing conditionally activated, masked biologics designed to be localized to the tumor microenvironment. The Company is developing a pipeline of localized biologics, through its PROBODY therapeutic platform. Its pipeline comprises therapeutic candidates across multiple treatment modalities, including ADCs, T-cell engagers, and immune modulators such as cytokines. Its clinical-stage pipeline includes CX-2051, CX-904 and CX-801. CX-2051 is a masked, conditionally activated ADC directed toward EpCAM, armed with a topoisomerase-1 inhibitor payload. CX-904 is a masked, conditionally activated T-cell-engaging bispecific antibody targeting the EGFR on tumor cells and the CD3 receptor on T cells. CX-801 is a masked interferon alpha-2b PROBODY cytokine with broad potential applicability in traditionally immuno-oncology-sensitive as well as insensitive (cold) tumors.

What is the price predicton of CTMX Stock?

Wall Street analysts forecast CTMX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for CTMX is9.00 USD with a low forecast of 6.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is CytomX Therapeutics Inc (CTMX)'s revenue for the last quarter?

CytomX Therapeutics Inc revenue for the last quarter amounts to 10.26M USD, decreased -79.85

What is CytomX Therapeutics Inc (CTMX)'s earnings per share (EPS) for the last quarter?

CytomX Therapeutics Inc. EPS for the last quarter amounts to -0.10 USD, decreased -137.04

How many employees does CytomX Therapeutics Inc (CTMX). have?

CytomX Therapeutics Inc (CTMX) has 69 emplpoyees as of July 08 2026.

What is CytomX Therapeutics Inc (CTMX) market cap?

Today CTMX has the market capitalization of 835.98M USD.