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DFTX Overview

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ET
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ET
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Intellectia

Loading chart...

High
45.380
Open
44.350
VWAP
44.12
Vol
2.59M
Mkt Cap
5.77B
Low
42.500
Amount
114.19M
EV/EBITDA(TTM)
--
Total Shares
129.66M
EV
5.19B
EV/OCF(TTM)
--
P/S(TTM)
--
Definium Therapeutics, Inc., formerly Mind Medicine (MindMed) Inc., is engaged in developing therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. The Company plans to advance DT1201 ODT toward FDA submissions in the two largest psychiatric markets, generalized anxiety disorder (GAD) and major depressive disorder (MDD). Its late-stage pipeline includes four Phase 3 trials, two each for GAD and MDD, anchored by its lead candidate, DT120 ODT, which has received an FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is engaged in advancing its commercial strategy and operational readiness to support a care model and prepare for the launch of DT120 ODT, if approved and marketed. It also continues to advance its early-stage pipeline, having dosed the first patient in a Phase 2a study of DT4023 in adults with autism spectrum disorder (ASD).
Show More

Events Timeline

(ET)
2026-07-02
10:00:00
Helus Pharma Reports FY26 Results with $157.3M Cash
select
2026-06-25 (ET)
2026-06-25
10:30:00
Definium Reports Emerge Study Meets Primary Endpoint
select
2026-06-24 (ET)
2026-06-24
12:30:00
Definium Therapeutics Stock Rises 21.8% to $44.06
select
2026-06-24
10:30:00
Definium Therapeutics Stock Rises 17.7% to $42.58
select
2026-06-24
06:30:00
Deal Size Increased to $700M in Common Stock
select
2026-06-22 (ET)
2026-06-22
20:00:00
Tech Stocks Weighed Down, Nasdaq Falls Over 1%
select
2026-06-22
16:30:00
Nasdaq Declines Amid Weakness in Tech Stocks
select

News

Newsfilter
8.5
06-30Newsfilter
Rapid Growth in Major Depressive Disorder Treatment Market
  • Market Growth Potential: The global Major Depressive Disorder treatment market is projected to grow from approximately $20 billion in 2026 to nearly $36 billion by 2033, reflecting strong long-term demand and attracting billions in investment.
  • Clinical Trial Progress: Helus Pharma's HLP003 has surpassed 88% enrollment in the Phase 3 APPROACH study for MDD, with topline data expected in Q4 2026, marking a significant step towards commercialization.
  • Significant Efficacy: Phase 2 data for HLP003 demonstrated a ~23-point reduction in MADRS score at 12 months after two 16mg doses, achieving a 100% response rate and 71% remission rate, indicating its potential in treating treatment-resistant depression.
  • Strategic Partnerships: Helus Pharma has partnered with TARA Mind to enhance access to mental health treatment for veterans and collaborates with leading mental health organizations to support HLP003 Phase 3 recruitment, further expanding its market impact.
NASDAQ.COM
8.5
06-26NASDAQ.COM
Biotech Sector Update: FDA and EU Approvals
  • FDA Drug Approval: Ionis Pharmaceuticals' TRYNGOLZA received FDA approval as an adjunct therapy for severe hypertriglyceridemia, with Phase 3 studies showing up to a 72% reduction in triglycerides, significantly improving patient health and expected to drive revenue growth.
  • EU Therapy Approval: Merck's Keytruda in combination with Padcev received European approval for muscle-invasive bladder cancer, with Phase 3 trial data indicating a 60% improvement in event-free survival, laying the groundwork for market expansion in Europe.
  • New Treatment Launch: Gilead Sciences' Trodelvy was approved by the FDA as a first-line treatment for metastatic triple-negative breast cancer, demonstrating a 38% reduction in the risk of disease progression or death, projected to boost sales to $1.4 billion in 2025.
  • Strategic Restructuring and Layoffs: ADC Therapeutics announced a 17% workforce reduction, expected to save $10 million annually, aimed at reallocating resources to advance the ZYNLONTA project, although facing $3 million in severance costs in the short term, it is expected to enhance long-term financial health.
PRnewswire
8.5
06-26PRnewswire
Helus Pharma's HLP003 Phase 3 Trial Enrollment Surpasses 86%
  • Enrollment Milestone: Helus Pharma's HLP003 Phase 3 trial has surpassed 86% enrollment, keeping the FDA Breakthrough-designated program on track for a topline data readout in Q4 2026, indicating the company's potential in the mental health treatment space.
  • Clinical Trial Significance: Eric So noted that the continued enrollment progress underscores the execution of the clinical program, bringing them closer to the anticipated topline data release, which could provide a transformative treatment option for patients with major depressive disorder, enhancing the company's position in a competitive market.
  • FDA Breakthrough Designation: HLP003 has received FDA Breakthrough Therapy Designation, aimed at expediting development and review, signaling significant improvement potential in treating major depressive disorder, thus boosting investor confidence in the program.
  • Strong Market Demand: Major depressive disorder affects hundreds of millions globally, with traditional treatments offering limited relief; if HLP003 can validate its efficacy in Phase 3 trials, it could reshape the management of depression.
Newsfilter
8.5
06-26Newsfilter
Helus Pharma's HLP003 Phase 3 Trial Surpasses 86% Enrollment
  • Significant Trial Progress: Helus Pharma's HLP003 Phase 3 trial has surpassed 86% enrollment, keeping the FDA Breakthrough Therapy program on track for a topline data readout in Q4 2026, potentially offering a new treatment option for depression.
  • Clinical Data Highlights: HLP003 demonstrated substantial efficacy in Phase 2 trials, with a ~23-point reduction in MADRS scores at 12 months, and an 18-week response rate of 75%, improving to 100% at 12 months, laying a solid foundation for the upcoming Phase 3 trial.
  • Strong Market Demand: With millions affected by major depressive disorder and existing treatments often inadequate, HLP003's fast-acting, neuroplasticity-oriented approach could reshape depression management, addressing the urgent need for novel therapies in the market.
  • Far-reaching Strategic Implications: The Breakthrough Therapy designation accelerates HLP003's development, positioning Helus Pharma to carve out a niche in a competitive landscape, and successful Phase 3 data could pave the way for future commercialization efforts.
NASDAQ.COM
8.5
06-24NASDAQ.COM
Definium Therapeutics Prices $700 Million Public Offering for Psychiatric Drug Development
  • Public Offering Pricing: Definium Therapeutics has priced a public offering of 20.59 million common shares at $34 per share, expecting gross proceeds of approximately $700 million, which will significantly support its funding for psychiatric and neurological drug development.
  • Clinical Trial Progress: The company announced that its lead candidate DT120 met all primary and key secondary efficacy endpoints in the Phase 3 Emerge study for major depressive disorder, indicating its potential in mental health treatment and possibly enhancing future market acceptance.
  • Use of Proceeds: Definium intends to utilize the net proceeds from this offering for the research and development of DT120 ODT, commercialization preparations, and general corporate purposes, which will help accelerate its product launch and strengthen its market competitiveness.
  • Market Performance: As of March 31, 2026, Definium had $373.4 million in cash and cash equivalents, with its stock trading between a 52-week low of $6.40 and a high of $39.16, reflecting its market volatility and investor interest.
seekingalpha
8.5
06-24seekingalpha
Definium Therapeutics Prices $700M Public Offering of Common Shares
  • Upsized Offering: Definium Therapeutics has announced the pricing of 20.59 million common shares at $34.00 each, expected to generate approximately $700 million in gross proceeds before underwriting discounts, exceeding the initial $500 million target, indicating strong market demand for its products.
  • Clear Use of Proceeds: The funds raised will be allocated towards research and development, specifically for potential commercialization activities of DT120 ODT if approved, as well as for working capital and general purposes, reflecting the company's strategic planning for future growth.
  • Underwriter's Option: Definium has granted underwriters a 30-day option to purchase up to 3.09 million additional shares at the same price, which may enhance the fundraising capability and support ongoing investments in R&D.
  • Closing Timeline: The offering is expected to close around June 25, 2026, pending normal closing conditions, demonstrating the company's proactive approach in the capital markets to secure funding for future product development.
Wall Street analysts forecast DFTX stock price to rise
9 Analyst Rating
Wall Street analysts forecast DFTX stock price to rise
9 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
20.00
Averages
35.89
High
61.00
Current: 0.000
sliders
Low
20.00
Averages
35.89
High
61.00
Canaccord
Buy
maintain
$60 -> $58
AI Analysis
2026-06-30
Reason
Canaccord
Price Target
$60 -> $58
AI Analysis
2026-06-30
maintain
Buy
Reason
Canaccord lowered the firm's price target on Definium Therapeutics to $58 from $60 and keeps a Buy rating on the shares. The firm noted the company recently reported stellar Phase 3 data from its Emerge trial for DT120 (LSD d-tartrate orally-disintegrating tablet/ODT) for major depressive disorder (MDD) which was greeted enthusiastically by investors leading the compmany to raise about $805M on the back of the news. They adjusted the model on the recent capital raise and the increased share count.
JonesResearch
Buy
maintain
$61 -> $74
2026-06-24
Reason
JonesResearch
Price Target
$61 -> $74
2026-06-24
maintain
Buy
Reason
JonesResearch raised the firm's price target on Definium Therapeutics to $74 from $61 and keeps a Buy rating on the shares after the company announced the Phase III Emerge trial of DT120 in major depressive disorder met its primary endpoint. The results "were not only statistically significant, but achieved an impressive magnitude of effect," the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for DFTX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Definium Therapeutics Inc (DFTX.O) is 0.00, compared to its 5-year average forward P/E of --. For a more detailed relative valuation and DCF analysis to assess Definium Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
Current PE
0.00
Overvalued PE
Undervalued PE

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
Undervalued EV/EBITDA

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
81.98
Current PS
182.79
Overvalued PS
117.27
Undervalued PS
46.69

Financials

AI Analysis
Annual
Quarterly

Whales Holding DFTX

C
Commodore Capital LP
Holding
DFTX
+22.07%
3M Return
D
Driehaus Capital Management LLC
Holding
DFTX
+21.50%
3M Return
A
Avoro Capital Advisors LLC
Holding
DFTX
+17.64%
3M Return
V
Vestal Point Capital, LP
Holding
DFTX
+11.31%
3M Return

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Frequently Asked Questions

What is Definium Therapeutics Inc (DFTX) stock price today?

The current price of DFTX is 44.48 USD — it has increased 0.34

What is Definium Therapeutics Inc (DFTX)'s business?

Definium Therapeutics, Inc., formerly Mind Medicine (MindMed) Inc., is engaged in developing therapeutics intended to solve the underlying causes of psychiatric and neurological disorders and offer patients long-term remission rather than transient symptom reduction. The Company plans to advance DT1201 ODT toward FDA submissions in the two largest psychiatric markets, generalized anxiety disorder (GAD) and major depressive disorder (MDD). Its late-stage pipeline includes four Phase 3 trials, two each for GAD and MDD, anchored by its lead candidate, DT120 ODT, which has received an FDA Breakthrough Therapy Designation for GAD. In parallel, the Company is engaged in advancing its commercial strategy and operational readiness to support a care model and prepare for the launch of DT120 ODT, if approved and marketed. It also continues to advance its early-stage pipeline, having dosed the first patient in a Phase 2a study of DT4023 in adults with autism spectrum disorder (ASD).

What is the price predicton of DFTX Stock?

Wall Street analysts forecast DFTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for DFTX is35.89 USD with a low forecast of 20.00 USD and a high forecast of 61.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Definium Therapeutics Inc (DFTX)'s revenue for the last quarter?

Definium Therapeutics Inc revenue for the last quarter amounts to -59.22M USD, increased 84.15

What is Definium Therapeutics Inc (DFTX)'s earnings per share (EPS) for the last quarter?

Definium Therapeutics Inc. EPS for the last quarter amounts to -42631000.00 USD, increased 44.91

How many employees does Definium Therapeutics Inc (DFTX). have?

Definium Therapeutics Inc (DFTX) has 105 emplpoyees as of July 08 2026.

What is Definium Therapeutics Inc (DFTX) market cap?

Today DFTX has the market capitalization of 5.77B USD.