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ENTX Overview

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Intellectia

Loading chart...

High
1.720
Open
1.720
VWAP
1.66
Vol
226.09K
Mkt Cap
81.82M
Low
1.610
Amount
376.06K
EV/EBITDA(TTM)
--
Total Shares
49.29M
EV
80.15M
EV/OCF(TTM)
--
P/S(TTM)
--
Entera Bio Ltd is an Israel-based clinical-stage biopharmaceutical company focused on the development and commercialization of orally delivered large molecule therapeutics for use in areas with unmet medical need and where adoption of injectable therapies is limited due to cost, convenience and compliance challenges for patients. The Company developed a platform that enables the oral delivery of injectable proteins and large molecules. Entera Bio candidates are EB613 for the treatment of osteoporosis and EB612 for the treatment of hypoparathyroidism. Both EB613 and EB612 are oral formulations of human parathyroid hormone (1-34), or Parathormon (PTH). The products are administered via injection.
Show More

Events Timeline

(ET)
2026-06-22
10:00:00
Entera Bio Receives FDA Feedback on EB613
select
2026-05-08 (ET)
2026-05-08
16:30:00
Entera Bio Files to Sell 19.57M Ordinary Shares
select
2026-03-04 (ET)
2026-03-04
08:40:00
Entera Bio Submits Clinical Amendment for EB613
select
2026-02-09 (ET)
2026-02-09
09:00:00
Entera Bio Appoints Geno Germano as Chairman of the Board
select
2026-02-04 (ET)
2026-02-04
08:20:00
OPKO Health Expands Collaboration Agreement with Entera Bio
select
2026-01-21 (ET)
2026-01-21
08:40:00
Entera Bio Expects Corporate Milestones in Q1 2026
select
2025-12-23 (ET)
2025-12-23
08:50:00
Entera Bio Welcomes FDA Qualification of Bone Density as Regulatory Endpoint for New Drugs
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News

Newsfilter
8.5
06-23Newsfilter
Entera Bio Receives Positive FDA Feedback for EB613 Phase 3 Trial Approval
  • Regulatory Breakthrough: Entera Bio announced that the FDA has provided positive feedback on its EB613 registrational Phase 3 trial protocol, marking a significant step in the development of oral osteoporosis treatments, with the potential to become the first oral anabolic therapy in the market.
  • Clinical Design Approval: The FDA accepted Entera Bio's proposed design for a randomized, double-blind, placebo-controlled Phase 3 study involving approximately 750 postmenopausal women, with total hip bone mineral density at 12 months as the primary endpoint, laying the groundwork for a future New Drug Application.
  • Significant Market Potential: With around 200 million women affected by osteoporosis globally and over 2 million fractures occurring annually in the U.S., Entera Bio's EB613 aims to address the low adoption rates of existing injectable therapies, potentially expanding the patient base significantly.
  • Diversified Product Pipeline: In addition to EB613, Entera Bio is advancing multiple oral peptide drugs, including EB612 and EB618, showcasing its robust platform capabilities in oral peptide technology, which enhances the company's competitive position in the market.
stocktwits
9.0
06-22stocktwits
Entera Bio's Bone Density Treatment Trial Progress
  • FDA Support for New Trial: The U.S. FDA has approved Entera Bio's EB613 for a single large late-stage clinical trial, aiming to enroll approximately 750 postmenopausal women, which is a significant advancement in the treatment of osteoporosis and supports the company's path toward FDA approval.
  • Accelerated Timeline: Entera expects to begin the trial in late 2026 and report top-line results in the second half of 2028, about a year earlier than previously planned, which will expedite the product's market entry and enhance its competitive position.
  • Significant Early Study Results: The company's earlier mid-stage study involving 161 postmenopausal women demonstrated meaningful increases in bone density at the spine and hip, indicating the potential of EB613 in osteoporosis treatment and likely attracting more patients to its use.
  • Market Sentiment Shift: ENTX shares surged 52% following FDA feedback, with retail investor sentiment jumping from 'bullish' to 'extremely bullish', while analysts rated the stock a 'Buy' with a price target of $9, suggesting a potential upside of about 643%, reflecting strong market confidence in the drug.
Newsfilter
9.0
06-22Newsfilter
Entera Bio Initiates Phase 3 Trial for EB613 in Osteoporosis
  • Positive FDA Feedback: Entera Bio has received positive feedback from the FDA regarding the Phase 3 registration protocol for EB613, planning a randomized double-blind trial in 750 postmenopausal women to assess changes in hip bone mineral density at 12 months, supporting its New Drug Application (NDA).
  • Clinical Trial Design: The Phase 3 trial is expected to initiate in late 2026, with topline data anticipated in the second half of 2028, and EB613's clinical effectiveness is projected to be comparable to Forteo®, potentially achieving a 60% to 80% relative reduction in vertebral fracture risk.
  • Safety and Durability Study: Entera plans to submit 12-month data in its NDA and follow patients for 24 months in an open-label extension study to further evaluate EB613's safety and durability of treatment effect, enhancing its competitive position in the market.
  • Significant Market Potential: With over 2 million fractures occurring annually in the U.S., the development of EB613 as the first oral anabolic treatment aims to provide a more convenient therapeutic option for postmenopausal women, addressing the growing market demand.
Newsfilter
8.5
06-16Newsfilter
Entera Bio Reports Preclinical Data for EB612 and EB618
  • EB612 Clinical Data: Entera Bio's EB612 demonstrated robust bioavailability and sustained calcium increases across three preclinical models, with an IND application expected by late 2026, marking a significant advancement in treating hypoparathyroidism.
  • Good Tolerability: In non-human primate models, a single oral dose of EB612 significantly raised serum calcium levels for three days without safety concerns, laying a solid foundation for its future clinical applications.
  • EB618 Efficacy: As the first dual GLP-1/glucagon receptor agonist, EB618 exhibited dose-proportional pharmacokinetics in non-human primates and showed good tolerability even at doses exceeding the anticipated clinical range, supporting its potential in obesity and metabolic disorder treatments.
  • Collaborative Development Strategy: Entera's partnership with OPKO Health has expanded, with both companies advancing EB612 on a 50/50 basis, showcasing Entera's strong R&D capabilities and market prospects in the oral peptide drug sector.
Newsfilter
8.5
04-20Newsfilter
Entera Bio Hosts KOL Roundtable on EB613 for Osteoporosis
  • Significant Treatment Gap: Approximately two million osteoporotic fractures occur annually in the U.S., and while 92% of gynecologists would prescribe anabolic therapy if an oral option were available, only 12% currently use injectable anabolic agents, highlighting a substantial treatment gap.
  • Clinical Potential of EB613: As the first oral anabolic agent, EB613 stimulates bone formation while suppressing bone breakdown, with six-month bone density increments comparable to injectable PTH, potentially transforming the current treatment paradigm.
  • Clinical Trial Plans: Entera Bio intends to advance EB613 into Phase 3 trials imminently, designed to evaluate its efficacy both as a monotherapy and in combination with anti-resorptive agents, further validating its application in osteoporosis treatment.
  • Increased Patient Acceptance: The oral formulation of EB613 is expected to reduce patient resistance to injectable therapies, significantly enhancing treatment adherence and thereby improving bone health and quality of life.
Newsfilter
8.5
04-06Newsfilter
Entera Bio Secures $10 Million in Private Placement Financing
  • Financing Size: Entera Bio successfully issued 7,827,789 units at a price of $1.2775 per unit, raising approximately $10 million, reflecting strong market confidence in its biotechnology developments.
  • Potential Gains: If all warrants issued are exercised for cash, Entera could receive an additional $14.5 million, leading to total potential proceeds of approximately $24.5 million, thereby enhancing its financial strength to support R&D.
  • Use of Funds: The net proceeds from this financing will be used to initiate the Phase 3 registrational study of EB613 targeting osteoporosis in postmenopausal women, as well as for working capital and general corporate purposes, ensuring the company's ongoing development.
  • Legal Support: Greenberg Traurig advised Entera on this transaction, led by Drew M. Altman, showcasing the firm's expertise and influence in the biotechnology sector.
Wall Street analysts forecast ENTX stock price to rise
1 Analyst Rating
Wall Street analysts forecast ENTX stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
10.00
Averages
10.00
High
10.00
Current: 0.000
sliders
Low
10.00
Averages
10.00
High
10.00
H.C. Wainwright
Buy
to
Buy
downgrade
$10 -> $9
AI Analysis
2026-04-27
Reason
H.C. Wainwright
Price Target
$10 -> $9
AI Analysis
2026-04-27
downgrade
Buy
to
Buy
Reason
H.C. Wainwright lowered the firm's price target on Entera Bio to $9 from $10 and keeps a Buy rating on the shares.

Valuation Metrics

The current forward P/E ratio for Entera Bio Ltd (ENTX.O) is 0.00, compared to its 5-year average forward P/E of -4.14. For a more detailed relative valuation and DCF analysis to assess Entera Bio Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.14
Current PE
0.00
Overvalued PE
-1.89
Undervalued PE
-6.40

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1237.33
Current PS
0.00
Overvalued PS
3708.56
Undervalued PS
-1233.91

Financials

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Frequently Asked Questions

What is Entera Bio Ltd (ENTX) stock price today?

The current price of ENTX is 1.66 USD — it has decreased -2.92

What is Entera Bio Ltd (ENTX)'s business?

Entera Bio Ltd is an Israel-based clinical-stage biopharmaceutical company focused on the development and commercialization of orally delivered large molecule therapeutics for use in areas with unmet medical need and where adoption of injectable therapies is limited due to cost, convenience and compliance challenges for patients. The Company developed a platform that enables the oral delivery of injectable proteins and large molecules. Entera Bio candidates are EB613 for the treatment of osteoporosis and EB612 for the treatment of hypoparathyroidism. Both EB613 and EB612 are oral formulations of human parathyroid hormone (1-34), or Parathormon (PTH). The products are administered via injection.

What is the price predicton of ENTX Stock?

Wall Street analysts forecast ENTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ENTX is10.00 USD with a low forecast of 10.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Entera Bio Ltd (ENTX)'s revenue for the last quarter?

Entera Bio Ltd revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Entera Bio Ltd (ENTX)'s earnings per share (EPS) for the last quarter?

Entera Bio Ltd. EPS for the last quarter amounts to -0.07 USD, increased 16.67

How many employees does Entera Bio Ltd (ENTX). have?

Entera Bio Ltd (ENTX) has 20 emplpoyees as of July 08 2026.

What is Entera Bio Ltd (ENTX) market cap?

Today ENTX has the market capitalization of 81.82M USD.