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PBLS Overview

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Intellectia

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High
31.508
Open
29.450
VWAP
30.08
Vol
508.64K
Mkt Cap
3.69B
Low
28.390
Amount
15.30M
EV/EBITDA(TTM)
--
Total Shares
121.59M
EV
--
EV/OCF(TTM)
--
P/S(TTM)
--
Parabilis Medicines, Inc., formerly FOG Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company. It is built to develop transformative medicines addressing undruggable protein targets driving human disease. It leverages a proprietary platform to a novel therapeutic modality, Helicons, which are stabilized helical peptides engineered to bind and precisely modulate proteins that reach conventional medicine. Its lead product candidate, zolucatetide, is the first and only investigational therapy that inhibits the b-catenin: TCF interaction, the critical downstream node of the Wnt/b-catenin pathway. Its preclinical pipeline provides Helicon approach and includes programs targeting two key drivers of prostate cancer, the ETS-related gene and the androgen receptor (AR) in its active state (ARON). Helicon discovery platform integrates advanced AI and physics-based computational modeling with peptide synthesis and experimental screening to discover and develop drug candidates.
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Events Timeline

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News

CNBC
6.0
07-06CNBC
Key Wall Street Rating Updates on Monday
  • Wise Rating Upgrade: JPMorgan upgraded Wise to overweight, expecting net revenue growth in Q1 and Q2 to exceed mid-term guidance, indicating significant positive momentum in user activity and transaction volumes, which could drive stock price appreciation.
  • AMD Price Target Increase: Goldman Sachs raised AMD's price target from $450 to $640, believing strong performance in server CPUs will drive quarterly results, despite potential headwinds in the PC segment, maintaining an overall bullish outlook.
  • Netflix Price Target Downgrade: Goldman lowered Netflix's price target from $120 to $110 while maintaining a buy rating, anticipating upcoming earnings to face challenges in user growth and engagement due to seasonal factors and content scheduling impacts.
  • IBM Price Target Increase: Bank of America raised IBM's price target from $315 to $330, noting the company's shift towards higher-margin software and M&A activities driving strong free cash flow, indicating potential for future growth.
NASDAQ.COM
8.5
06-28NASDAQ.COM
Parabilis IPO Outperforms SpaceX's Debut
  • Strong IPO Performance: Parabilis Medicines' IPO on June 10 saw its shares close up 58% from the $20 offer price, outperforming SpaceX's debut increase of 19%, although such performance does not guarantee future success.
  • Significant Technical Challenges: The Helicons technology developed by Parabilis aims to target traditionally undruggable proteins, but the biopharma industry's history indicates that developing successful drugs in this area is fraught with difficulties, necessitating caution from investors.
  • Clinical Trial Progress: The lead candidate zolucatetide is set to enter phase 3 trials in 2027, with recent phase 1/2 trial data showing tumor reductions in all 25 evaluable patients and a 74% objective response rate, yet the single-arm design and limited follow-up raise concerns about the reliability of these results.
  • Support from Partners: Parabilis secured a collaboration agreement with Regeneron Pharmaceuticals in May 2026, which includes $50 million in cash and $75 million in equity, along with up to $2.2 billion in milestone payments, indicating the potential value and market recognition of its platform technology.
Fool
8.5
06-28Fool
Parabilis Medicines IPO Surges 58%, Outpacing SpaceX
  • IPO Performance: Parabilis Medicines debuted on June 10, closing up 58% from its $20 offer price, indicating strong market interest, although investors should carefully assess its long-term value compared to SpaceX's 19% rise.
  • Technical Challenges: The company is developing a Helicons platform aimed at targeting flat protein surfaces that are traditionally undruggable, a goal that, while appealing, has seen many failures in the biopharma industry, necessitating investor caution regarding its feasibility.
  • Clinical Trial Progress: Its lead candidate, zolucatetide, is set to enter phase 3 trials in 2027, and recent phase 1/2 trial data showed a 74% objective response rate among 25 evaluable patients with desmoid tumors, although the single-arm design and limited follow-up raise concerns about data robustness.
  • Collaborative Outlook: Parabilis has secured a $50 million collaboration with Regeneron Pharmaceuticals, including $75 million in equity and up to $2.2 billion in milestone payments, signaling confidence in its platform's potential value, though investors should remain cautious.
Fool
8.5
06-20Fool
Parabilis Medicines Director Increases Shareholding
  • Share Purchase Details: Director Alan Sebulsky of Parabilis Medicines bought 17,500 shares on June 12 and 15, 2026, for approximately $474,000, indicating strong confidence in the company's future prospects.
  • Indirect Holdings Increase: Following the transaction, Sebulsky's direct holdings remained at zero, while his indirect holdings via Apothecary Capital LLC rose to 30,000 shares, reflecting a positive outlook on the company's long-term growth.
  • Price Analysis: The weighted average purchase price of $27.06 per share was about 8.2% above the market close of $25.85 on June 15, highlighting strong market demand for Parabilis shares.
  • Investor Signal: As a well-regarded biotech investor, Sebulsky's purchase is seen as a bullish indicator for Parabilis's future, especially following its recent IPO, as he is willing to invest at a price above the IPO level.
NASDAQ.COM
8.5
06-20NASDAQ.COM
Parabilis Director's Share Purchase Signals Bullish Outlook
  • Share Acquisition: Director Alan Sebulsky purchased 17,500 shares on June 12 and 15 at a weighted average price of $27.06, totaling approximately $474,000, increasing his ownership to 30,000 shares, which signals confidence in the company's future.
  • IPO Performance: Parabilis successfully went public on June 10 at $20 per share, with an upsized IPO indicating strong investor demand, which further enhances market optimism regarding its prospects.
  • Insider Signal: Sebulsky's purchase is viewed as a bullish signal for the company's future, especially since he bought shares at a price higher than the IPO price, reflecting his recognition of the company's value.
  • Equity Incentives: Sebulsky has also been granted 39,792 stock options that will vest over the next 36 months, further demonstrating his commitment to the long-term growth of Parabilis.
NASDAQ.COM
5.0
06-18NASDAQ.COM
Insider Buying Analysis: PBLS and ABTC
  • Parabilis Medicines Insider Buy: Alan Sebulsky made a notable purchase of 17,500 shares of PBLS at $27.06 each for a total of $473,529 on Monday, despite the stock trading as low as $25.35 on Thursday, which is 6.3% below his purchase price; however, the stock rose about 2% on the same day, indicating market optimism about its future prospects.
  • Historical Purchase Record: Prior to this latest buy, Sebulsky had purchased 250,000 shares of PBLS at $20.00 each over the past year, reflecting his confidence in the company's long-term value, which may attract further investor interest in the stock.
  • American Bitcoin Insider Buy: Richard Busch purchased 450,000 shares of ABTC at $0.87 each for a total investment of $391,500 on Monday, even as the stock traded down to $0.83 on Thursday, which is 4.7% below his purchase price, suggesting his optimistic outlook on the company's growth potential.
  • Historical Purchase Record: Before this transaction, Busch had made four other purchases of ABTC over the past year, totaling $902,580 at an average price of $1.34 per share, demonstrating his sustained confidence in the company, which could draw more investor attention.
Wall Street analysts forecast PBLS stock price to rise
0 Analyst Rating
Wall Street analysts forecast PBLS stock price to rise
0 Buy
0 Hold
0 Sell
Current: 0.000
sliders
Low
Averages
High
Current: 0.000
sliders
Low
Averages
High
Leerink
Outperform
initiated
$40
AI Analysis
2026-07-06
New
Reason
Leerink
Price Target
$40
AI Analysis
2026-07-06
New
initiated
Outperform
Reason
Leerink initiated coverage of Parabilis Medicines with an Outperform rating and $40 price target. The firm believes the company's lead asset zolucatetide has the potential to be active across a number of Wnt-driven tumors, with over $10B in peak WW sales by 2045 in its forecasts. Continued derisking of zolucatetide and Parabilis' broader Helicon pipeline is expected to drive significant fundamental and strategic value, Leerink adds.
Evercore ISI
analyst
Outperform
initiated
$NULL
2026-07-06
New
Reason
Evercore ISI
analyst
Price Target
$NULL
2026-07-06
New
initiated
Outperform
Reason
Evercore ISI initiated coverage of Parabilis Medicines with an Outperform rating and no price target. Parabilis is \"taking bold strides in drug development,\" initial findings in desmoid tumors are \"promising,\" and the swift progression to Phase 3 \"highlights their commitment,\" the analyst tells investors. Beyond immediate indications, Parabilis is exploring orphan tumors like ACP and assessing larger cohorts, including hepatocellular carcinoma, the analyst added.
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Valuation Metrics

The current forward P/E ratio for Parabilis Medicines Inc (PBLS.O) is 0.00, compared to its 5-year average forward P/E of --. For a more detailed relative valuation and DCF analysis to assess Parabilis Medicines Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
Current PE
0.00
Overvalued PE
Undervalued PE

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
Undervalued EV/EBITDA

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
Current PS
0.00
Overvalued PS
Undervalued PS

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Frequently Asked Questions

What is Parabilis Medicines Inc (PBLS) stock price today?

The current price of PBLS is 30.35 USD — it has increased 3.94

What is Parabilis Medicines Inc (PBLS)'s business?

Parabilis Medicines, Inc., formerly FOG Pharmaceuticals, Inc., is a clinical-stage biopharmaceutical company. It is built to develop transformative medicines addressing undruggable protein targets driving human disease. It leverages a proprietary platform to a novel therapeutic modality, Helicons, which are stabilized helical peptides engineered to bind and precisely modulate proteins that reach conventional medicine. Its lead product candidate, zolucatetide, is the first and only investigational therapy that inhibits the b-catenin: TCF interaction, the critical downstream node of the Wnt/b-catenin pathway. Its preclinical pipeline provides Helicon approach and includes programs targeting two key drivers of prostate cancer, the ETS-related gene and the androgen receptor (AR) in its active state (ARON). Helicon discovery platform integrates advanced AI and physics-based computational modeling with peptide synthesis and experimental screening to discover and develop drug candidates.

What is the price predicton of PBLS Stock?

Wall Street analysts forecast PBLS stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for PBLS is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Parabilis Medicines Inc (PBLS)'s revenue for the last quarter?

Parabilis Medicines Inc revenue for the last quarter amounts to NaN USD, decreased

What is Parabilis Medicines Inc (PBLS)'s earnings per share (EPS) for the last quarter?

Parabilis Medicines Inc. EPS for the last quarter amounts to USD, decreased

How many employees does Parabilis Medicines Inc (PBLS). have?

Parabilis Medicines Inc (PBLS) has 0 emplpoyees as of July 08 2026.

What is Parabilis Medicines Inc (PBLS) market cap?

Today PBLS has the market capitalization of 3.69B USD.