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PVLA Overview

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ET
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0.000
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ET
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Intellectia

Loading chart...

High
147.960
Open
141.490
VWAP
143.98
Vol
152.93K
Mkt Cap
2.09B
Low
138.290
Amount
22.02M
EV/EBITDA(TTM)
--
Total Shares
14.34M
EV
1.77B
EV/OCF(TTM)
--
P/S(TTM)
--
Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies. The Company is developing a pipeline of product candidates based on its patented QTORIN platform, with an initial focus on serious, rare genetic skin diseases, many of which are lifelong in nature. Its QTORIN product candidates are developed to accommodate the cargo at high concentrations in order to drive sufficient drug to its target deep in the epidermis and dermis. The Company's lead product candidate, QTORIN 3.9% rapamycin anhydrous gel (QTORIN rapamycin), is being evaluated in the Phase III SELVA clinical trial in microcystic lymphatic malformations and the Phase II TOIVA clinical trial in cutaneous venous malformations.
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Events Timeline

(ET)
2026-06-30
08:00:00
Palvella Therapeutics Appoints Matt Pauls to Board of Directors
select
2026-06-29 (ET)
2026-06-29
08:00:00
Palvella Submits NDA for Qtorin Drug
select
2026-06-22 (ET)
2026-06-22
08:01:00
Palvella Therapeutics Receives FDA Rolling Review for Qtorin
select
2026-06-03 (ET)
2026-06-03
07:40:00
Palvella Completes FDA Pre-NDA Meeting
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2026-05-27 (ET)
2026-05-27
07:50:00
Palvella Therapeutics Secures U.S. Patent for Qtorin Program
select
2026-05-20 (ET)
2026-05-20
16:40:00
Palvella Releases Qtorin Clinical Data, Plans FDA New Drug Application
select
2026-05-15 (ET)
2026-05-15
07:50:00
Palvella Therapeutics Releases New Data from Qtorin Clinical Trial
select
2026-05-07 (ET)
2026-05-07
09:20:00
Palvella Reports Q1 Cash and Investments at $261.9M
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2026-05-04 (ET)
2026-05-04
08:00:00
Palvella Therapeutics Begins LOTU Clinical Trial
select

News

Newsfilter
5.0
06-30Newsfilter
Palvella Appoints Matt Pauls to Board of Directors
  • New Board Member: Palvella Therapeutics has appointed Matt Pauls to its Board of Directors, leveraging his over 25 years of experience in the rare disease biopharmaceutical sector, which is expected to enhance the company's regulatory and commercialization efforts.
  • Extensive Industry Experience: Pauls has held executive roles at companies like Savara, Soleno, and Insmed, notably leading the successful commercialization of KEVEYIS® and Macrilen® at Strongbridge Biopharma, showcasing his deep expertise in product launch strategies.
  • Strategic Development Opportunity: As Palvella prepares for the potential launch of QTORIN™ rapamycin, Pauls' addition is poised to provide crucial support for the company's pipeline in rare skin diseases and vascular malformations, aiding in achieving market objectives.
  • Future Outlook: Pauls expressed strong conviction in Palvella's strategy and is eager to apply his extensive experience to drive rapid growth, particularly in areas lacking FDA-approved treatment options.
Newsfilter
8.5
06-29Newsfilter
Palvella Submits NDA for QTORIN™ Rapamycin
  • Rolling NDA Submission Initiated: Palvella Therapeutics has submitted the first module of its NDA for QTORIN™ 3.9% rapamycin anhydrous gel to the FDA, marking a significant step toward potential approval, with plans to complete the remaining modules in the second half of 2026, thereby accelerating treatment for patients with microcystic lymphatic malformations.
  • Significant Market Potential: QTORIN™ rapamycin is poised to become the first FDA-approved therapy for microcystic lymphatic malformations, addressing the urgent needs of over 30,000 patients in the U.S., and if approved, is expected to launch commercially in the first half of 2027, significantly enhancing the company's market position.
  • Clinical Trial Results Promising: The Phase 3 SELVA study demonstrated highly statistically significant improvements across primary and secondary endpoints, indicating the efficacy and good tolerability of QTORIN™ rapamycin in targeting microcystic lymphatic malformations, laying a solid foundation for future market promotion.
  • Strategic Partnerships and Awareness Campaign: Palvella has launched the BEYOND mLM campaign in collaboration with various organizations to raise awareness about microcystic lymphatic malformations, supporting early diagnosis and education, which will further enhance patient and physician acceptance of the new therapy and drive rapid market development.
Fool
5.0
06-27Fool
Palvella COO Sells Stock Options for $476,000
  • Stock Option Transaction: Kathleen Goin, COO of Palvella Therapeutics, exercised 4,302 stock options, converting them into common shares for a total transaction value of approximately $476,000, indicating the company's active engagement in the capital markets.
  • Ownership Change Analysis: While Goin's direct ownership of common stock has dropped to zero, she retains 17,219 outstanding options, preserving her economic interest in the company, particularly against the backdrop of rising stock prices.
  • Market Performance Review: The shares were sold at a weighted average price of around $110.73, while the stock price surged to $148.21 as of June 26, 2026, reflecting nearly a 620% annual increase, showcasing market optimism regarding QTORIN.
  • Regulatory Progress and Market Outlook: Palvella recently received FDA rolling review for its New Drug Application for QTORIN, with plans to complete the submission in the second half of 2026, and management aims to leverage Breakthrough Therapy and Fast Track designations to expedite the approval process, enhancing investor confidence in the company's future.
NASDAQ.COM
8.5
06-27NASDAQ.COM
Palvella Therapeutics Executive Exercises Stock Options
  • Stock Option Exercise: Kathleen Goin, COO of Palvella Therapeutics, exercised and sold 4,302 common shares on June 17, 2026, for approximately $476,000 at an average price of $110.73 per share, indicating executive confidence in the company's future stock performance.
  • FDA Review Progress: The company recently received FDA rolling review for its New Drug Application for QTORIN rapamycin, suggesting a positive regulatory outlook for its rare skin disease treatment, which could expedite the approval process and enhance market competitiveness.
  • Strong Market Performance: Palvella's shares have surged nearly 620% over the past year, reflecting investor optimism regarding its lead therapy QTORIN, further solidifying the company's position in the rare disease treatment market.
  • Strategic Market Shift: The recent move of Palvella's shares to the Nasdaq Global Market is expected to increase the company's visibility, aiding in garnering more attention and investment for its potential first-in-disease therapies.
Yahoo Finance
5.0
06-27Yahoo Finance
Palvella Therapeutics Executive Sells Stock Options for $476,000
  • Executive Transaction Overview: Kathleen Goin, COO of Palvella Therapeutics, exercised 4,302 stock options and immediately converted them into common shares for a transaction value of approximately $476,000, indicating proactive management of executive holdings.
  • Ownership Change Analysis: While Goin's direct ownership of common stock is now zero, she retains 17,219 outstanding options, preserving her economic interest through potential future share conversions, reflecting confidence in the company's growth trajectory.
  • Market Reaction and Stock Performance: The shares were sold at a weighted average price of $110.73, while the stock closed at $148.21 on June 26, 2026, showcasing a nearly 620% increase over the past year, highlighting market optimism surrounding QTORIN.
  • Regulatory and Future Outlook: Goin's transaction was executed under a Rule 10b5-1 trading plan adopted on August 19, 2025; despite insider sales, upcoming FDA rolling review and new drug application submission are likely to have a more significant impact on the company's commercialization prospects.
NASDAQ.COM
9.0
06-22NASDAQ.COM
Palvella Receives FDA Rolling Review for Qtorin Application
  • FDA Rolling Review: Palvella Therapeutics announced that its new drug application for Qtorin rapamycin has received a rolling review from the FDA, a process designed to expedite the evaluation of drugs for treating microcystic lymphatic malformations, indicating the FDA's recognition of the drug's potential efficacy.
  • Therapeutic Potential: Qtorin rapamycin is Palvella's lead candidate, designed to deliver rapamycin directly to pathogenic skin tissue to inhibit disease-driving mTOR signaling, expected to provide a new treatment option for mLM patients who currently have no FDA-approved therapies.
  • Clinical Trial Success: In the Phase 3 SELVA trial, Qtorin rapamycin successfully met its primary endpoint, demonstrating its efficacy in treating microcystic lymphatic malformations and laying the groundwork for the upcoming NDA submission.
  • Future Plans: Palvella plans to complete the NDA submission in the second half of 2026, further advancing Qtorin's market access, while the drug is also being developed for treating cutaneous venous malformations and clinically significant angiokeratomas, showcasing its broad application potential.
Wall Street analysts forecast PVLA stock price to rise
15 Analyst Rating
Wall Street analysts forecast PVLA stock price to rise
15 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
133.00
Averages
182.20
High
212.00
Current: 0.000
sliders
Low
133.00
Averages
182.20
High
212.00
Stephens
Stephens
initiated
$220
AI Analysis
2026-05-12
Reason
Stephens
Stephens
Price Target
$220
AI Analysis
2026-05-12
initiated
Reason
Stephens initiated coverage of Palvella Therapeutics with an Overweight rating and $220 price target. Palvella is a clinical-stage biopharmaceutical company leveraging its Qtorin platform to target rare genetic dermatologic conditions with no FDA approved therapies, the analyst tells investors in a research note. The firm says the company's lead asset, Qtorin rapamycin, is advancing across multiple indications. It believes the market underappreciates Palvella's potential penetration in the microcystic lymphatic malformations setting.
Chardan
Geulah Livshits
Buy
maintain
$210 -> $240
2026-03-31
Reason
Chardan
Geulah Livshits
Price Target
$210 -> $240
2026-03-31
maintain
Buy
Reason
Chardan analyst Geulah Livshits raised the firm's price target on Palvella Therapeutics to $240 from $210 and keeps a Buy rating on the shares. The company highlighted progress across its expanding topical therapy pipeline when reporting Q4 results, the analyst tells investors in a research note. The firm says Palvella's cash position should take it through initial approval and launch in microcystic lymphatic malformations.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PVLA
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Valuation Metrics

The current forward P/E ratio for Palvella Therapeutics Inc (PVLA.O) is 0.00, compared to its 5-year average forward P/E of -12.97. For a more detailed relative valuation and DCF analysis to assess Palvella Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-12.97
Current PE
0.00
Overvalued PE
-6.12
Undervalued PE
-19.81

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-10.17
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-2.75
Undervalued EV/EBITDA
-17.58

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
15489.37
Current PS
59.44
Overvalued PS
37553.35
Undervalued PS
-6574.62

Financials

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Whales Holding PVLA

S
Summit Partners Public Asset Management, LLC
Holding
PVLA
+37.64%
3M Return
B
BVF Partners L.P.
Holding
PVLA
+23.36%
3M Return
F
Frazier Life Sciences Management, LP
Holding
PVLA
+22.16%
3M Return
S
Suvretta Capital Management, LLC
Holding
PVLA
+21.79%
3M Return

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Frequently Asked Questions

What is Palvella Therapeutics Inc (PVLA) stock price today?

The current price of PVLA is 145.7 USD — it has increased 3.84

What is Palvella Therapeutics Inc (PVLA)'s business?

Palvella Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies to treat patients suffering from serious, rare genetic skin diseases for which there are no FDA-approved therapies. The Company is developing a pipeline of product candidates based on its patented QTORIN platform, with an initial focus on serious, rare genetic skin diseases, many of which are lifelong in nature. Its QTORIN product candidates are developed to accommodate the cargo at high concentrations in order to drive sufficient drug to its target deep in the epidermis and dermis. The Company's lead product candidate, QTORIN 3.9% rapamycin anhydrous gel (QTORIN rapamycin), is being evaluated in the Phase III SELVA clinical trial in microcystic lymphatic malformations and the Phase II TOIVA clinical trial in cutaneous venous malformations.

What is the price predicton of PVLA Stock?

Wall Street analysts forecast PVLA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PVLA is182.20 USD with a low forecast of 133.00 USD and a high forecast of 212.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Palvella Therapeutics Inc (PVLA)'s revenue for the last quarter?

Palvella Therapeutics Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Palvella Therapeutics Inc (PVLA)'s earnings per share (EPS) for the last quarter?

Palvella Therapeutics Inc. EPS for the last quarter amounts to -1.20 USD, increased 62.16

How many employees does Palvella Therapeutics Inc (PVLA). have?

Palvella Therapeutics Inc (PVLA) has 29 emplpoyees as of July 08 2026.

What is Palvella Therapeutics Inc (PVLA) market cap?

Today PVLA has the market capitalization of 2.09B USD.