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STRO Should I Buy

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Intellectia

Should You Buy Sutro Biopharma Inc (STRO) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
23.780
1 Day change
-4.38%
52 Week Range
26.540
Analysis Updated At
2026/04/03
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Given the investor's beginner level, long-term strategy, and available investment range, Sutro Biopharma Inc. (STRO) is not a strong buy at this moment. The technical indicators are mixed, with no clear bullish signals, and the company's financial performance shows significant declines in revenue, net income, and EPS. While analyst ratings and price target upgrades are positive, the lack of recent news, no significant trading trends, and weak proprietary trading signals suggest a cautious approach. Holding off for now is recommended.

Technical Analysis

The MACD is negatively expanding, indicating bearish momentum. RSI is neutral at 49.753, and moving averages are bullish (SMA_5 > SMA_20 > SMA_200). Key support is at 20.257, and resistance is at 25.785. Overall, the technical indicators are mixed, with no strong bullish signals.

Options Data

Bearish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
2
Buy
8

Positive Catalysts

  • Analyst upgrades with significant price target increases, particularly highlighting the potential of STRO-004 and its favorable pre-clinical profile. The company's precision-engineered platform is seen as a differentiator.

Neutral/Negative Catalysts

  • The company's financial performance in Q4 2025 showed significant declines in revenue (-21.35%), net income (-35.45%), and EPS (-39.07%). No recent news or significant trading trends from hedge funds, insiders, or Congress. Post-market price change is -1.60%, reflecting weak sentiment.

Financial Performance

In Q4 2025, revenue dropped to $11.65M (-21.35% YoY), net income dropped to -$46.76M (-35.45% YoY), and EPS dropped to -$5.35 (-39.07% YoY). Gross margin remained at 100%. Overall, financials indicate a challenging quarter with declining growth metrics.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Recent analyst upgrades are positive, with Deutsche Bank raising the price target to $55, Wells Fargo to $27, and H.C. Wainwright to $28. Analysts highlight the potential of STRO-004 and the company's platform as key drivers for future growth.

Wall Street analysts forecast STRO stock price to fall
7 Analyst Rating
Wall Street analysts forecast STRO stock price to fall
4 Buy
2 Hold
1 Sell
Moderate Buy
Current: 24.870
sliders
Low
8
Averages
20
High
51
Current: 24.870
sliders
Low
8
Averages
20
High
51
Deutsche Bank
Buy
maintain
$51 -> $55
AI Analysis
2026-03-25
Reason
Deutsche Bank
Price Target
$51 -> $55
AI Analysis
2026-03-25
maintain
Buy
Reason
Deutsche Bank raised the firm's price target on Sutro Biopharma to $55 from $51 and keeps a Buy rating on the shares. The firm says the company's Q4 report highlighted its execution with STRO-004 data in mid-2026.
Wells Fargo
Derek Archila
Equal Weight -> Overweight
upgrade
$8 -> $27
2026-03-24
Reason
Wells Fargo
Derek Archila
Price Target
$8 -> $27
2026-03-24
upgrade
Equal Weight -> Overweight
Reason
Wells Fargo analyst Derek Archila upgraded Sutro Biopharma to Overweight from Equal Weight with a price target of $27, up from $8, post the Q4 report. The update was positive with STRO-004 data on track for mid-2026, the analyst tells investors in a research note. Wells sees share upside on positive data for STRO-004 at current levels. STRO-004's pre-clinical profile demonstrated "early signs of differentiation" on ocular and skin toxicity that could translate to a favorable efficacy and safety profile, the analyst tells investors in a research note.
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