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AXSM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
252.600
Open
242.310
VWAP
247.41
Vol
1.06M
Mkt Cap
12.85B
Low
239.860
Amount
261.26M
EV/EBITDA(TTM)
--
Total Shares
51.46M
EV
12.38B
EV/OCF(TTM)
--
P/S(TTM)
17.24
Axsome Therapeutics, Inc. is a fully integrated biopharmaceutical company. The Company focused on developing medicines for people impacted by central nervous system (CNS) conditions. Its commercial products include AUVELITY, SUNOSI, and SYMBRAVO. It is also advancing pipeline of novel product candidates in early- to late-stage development addressing a broad range of serious neurological and psychiatric conditions. Its product pipelines include AXS-05, AXS-12, and AXS-14. Its lead product candidate, AXS-05 (dextromethorphan-bupropion), is developed for the treatment of Alzheimer’s disease (AD) agitation and smoking cessation. Its AXS-12 (reboxetine) is a novel, oral, potent, highly selective investigational norepinephrine reuptake inhibitor (NRI) and cortical dopamine modulator being developed for the treatment of narcolepsy. Its AXS-14 (esreboxetine) is a novel, oral, potent, highly selective investigational NRI being developed for the management of fibromyalgia.
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Events Timeline

(ET)
2026-06-26
07:30:00
Axsome Therapeutics Doses First Patient in FOCUS-3 Trial
select
2026-06-03 (ET)
2026-06-03
07:30:00
Axsome Therapeutics Resolves Sunosi Patent Litigation
select

News

Fool
7.5
07-06Fool
Biotech Stocks Outperform S&P 500 in H1 2026
  • Moderna's Recovery Potential: Moderna forecasts a revenue growth of up to 10% in 2026 and is awaiting regulatory approval for a new flu vaccine on August 5; despite expectations of a 40% price decline over the next 12 months, the launch of new products presents significant growth opportunities for the company.
  • Breakthrough Cancer Drug: Revolution Medicines reported unprecedented survival rates for its cancer drug Daraxonrasib in phase 3 trials and plans to submit for regulatory review; while Wall Street anticipates only a 2% price increase in the coming months, the drug's potential market impact is substantial.
  • Axsome's Growth Drivers: Axsome Therapeutics is expected to see a 13% price increase over the next year, driven by the approval of its drugs Auvelity and Symbravo, with ongoing phase 3 trials across five treatment areas that could lead to explosive earnings growth if successful.
  • Market Sentiment Shift: Despite overall market pressures from turmoil in Iran and rising oil prices, biotech stocks have thrived as investors shift towards new opportunities, reflecting strong demand and confidence in innovative therapies.
NASDAQ.COM
8.5
07-06NASDAQ.COM
Biotech Companies Reach Critical Turning Point
  • Moderna's Recovery Outlook: Moderna anticipates a revenue growth of up to 10% in 2026 and is awaiting potential approval for a flu vaccine on August 5, which could provide new growth momentum, although the market expects a 40% pullback in stock price over the next 12 months.
  • Revolution Medicines Breakthrough: Revolution Medicines reported significant results in phase 3 trials for its cancer drug, daraxonrasib, showing a median survival of 13.2 months in previously treated metastatic pancreatic cancer, far exceeding chemotherapy's 6.7 months, with plans to submit for regulatory review, indicating substantial future growth potential.
  • Axsome's Growth Potential: Axsome Therapeutics is expected to see a 13% stock price increase over the next 12 months, driven by its drugs Auvelity and Symbravo targeting agitation associated with Alzheimer's and migraines, respectively, while ongoing phase 3 trials could lead to explosive earnings growth if successful.
  • Market Dynamics Analysis: Despite the S&P 500's over 9% gain in the first half of 2026, biotech companies like Moderna, Revolution Medicines, and Axsome outperformed, reflecting investor interest in emerging opportunities, which may shift market funds towards these high-potential stocks.
Fool
9.5
07-02Fool
Axsome Therapeutics Shows Significant Growth Potential
  • Revenue Growth: Axsome Therapeutics reported a 59% increase in Auvelity revenue to $153 million this quarter, while Sunosi's revenue rose 34% to $33 million, demonstrating strong performance in the CNS drug market and solidifying its market position.
  • New Drug Launch Prospects: The company has submitted AXS-12 for narcolepsy regulatory review and is conducting phase three trials for solriamfetol across four indications, indicating that potential new product launches could significantly drive future revenue growth and bolster investor confidence.
  • Market Coverage Improvement: Currently, Symbravo's insurance coverage stands at 57%, compared to over 80% for other drugs, and the company is working to enhance this ratio, which is expected to positively impact future sales growth.
  • Strong Financial Position: With $305 million in cash reserves, Axsome is well-positioned to fund operations until achieving cash flow positivity, indicating a solid financial foundation for business expansion and new product development.
NASDAQ.COM
5.0
07-02NASDAQ.COM
Axsome's Auvelity Approved for Alzheimer's Agitation Treatment
  • Revenue Surge: Axsome's Auvelity generated $153 million in revenue last quarter, marking a 59% increase, indicating strong demand in the Alzheimer's-related drug market and reinforcing the company's position in the CNS disorders sector.
  • Sales Force Expansion: To enhance Auvelity's market penetration, Axsome has assembled a sales team of over 600, focusing on promoting the drug to primary care physicians, neurologists, and geriatric specialists, which is expected to significantly boost product awareness and sales.
  • New Drug Development: Axsome is advancing AXS-12 for narcolepsy through regulatory review, and solriamfetol is in phase three trials for four indications, which could provide robust support for the company's future revenue growth.
  • Strong Cash Position: With $305 million in cash reserves, Axsome is well-positioned to fund operations until achieving cash flow positivity, providing ample financial backing for future expansions and new product launches.
stocktwits
7.0
07-01stocktwits
Tarsus Accused of Market Manipulation by Culper Research
  • Short Seller Allegations: Culper Research has accused Tarsus Pharmaceuticals of using questionable practices to boost sales of its sole product, XDEMVY, resulting in a 5% drop in stock price on Wednesday, potentially marking its worst day since April.
  • Medicare Copay Scheme: Culper claims Tarsus has funded copay assistance for Medicare patients through the HealthWell Foundation, with donations of $5.7 million in 2023 and an expected $31.2 million in 2024, arguing this violates the Anti-Kickback Statute and poses legal risks.
  • Inflated Market Size: Tarsus has touted a 25 million patient opportunity for Demodex blepharitis, but a survey indicates only 18% of patients are diagnosed, leading Culper to estimate a true market size closer to 5 million, with peak annual revenues for XDEMVY projected below $800 million.
  • Financial Guidance Downgrade: Culper asserts that Tarsus is likely to miss its 2026 guidance, as analysts have underestimated rising patient assistance and other SG&A costs, which could lead to further declines in stock price in the future.
NASDAQ.COM
9.0
06-26NASDAQ.COM
Axosome Initiates Phase 3 Trial for Solriamfetol in ADHD Treatment
  • Trial Initiation: Axosome Therapeutics has announced the dosing of the first patient in the Phase 3 FOCUS-3 trial involving 486 ADHD patients, aimed at assessing the safety and efficacy of Solriamfetol over a 6-week period, indicating the company's proactive advancement in ADHD treatment.
  • Market Demand: With approximately 7 million children diagnosed with ADHD in the U.S., the potential market opportunity for Solriamfetol is significant, and successful outcomes could lead to substantial revenue growth for the company.
  • Drug Mechanism: Solriamfetol acts as a dopamine and norepinephrine reuptake inhibitor, offering multiple mechanisms of action that may provide new treatment options for ADHD, major depressive disorder, and other related conditions, thereby enhancing the company's competitive edge in the biopharmaceutical sector.
  • Stock Performance: Currently trading at $247, up 3.95%, Axosome's stock reflects positive market sentiment regarding its clinical trial progress, which could further bolster investor confidence and company valuation.
Wall Street analysts forecast AXSM stock price to rise
15 Analyst Rating
Wall Street analysts forecast AXSM stock price to rise
14 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
153.00
Averages
209.54
High
260.00
Current: 0.000
sliders
Low
153.00
Averages
209.54
High
260.00
RBC Capital
Leonid Timashev
Outperform
maintain
$302 -> $304
AI Analysis
2026-07-07
New
Reason
RBC Capital
Leonid Timashev
Price Target
$302 -> $304
AI Analysis
2026-07-07
New
maintain
Outperform
Reason
RBC Capital analyst Leonid Timashev raised the firm's price target on Axsome Therapeutics to $304 from $302 and keeps an Outperform rating on the shares as part of a broader research note previewing Q2 earnings in Biotech. The biotech sector has picked up considerable momentum, with a near-unprecedented two-week move in June relative to the S&P - driven by strong data expanding innovative spaces and perceptions around improving FDA flexibility/stability - and with outlooks more concretely definable than other high-volatility spaces, capital could continue to flow in, the analyst tells investors in a research note. Q2 earnings are shaping up to be seasonally strong, and with multiple opportunities for beats and the M&A resurgence likely to continue, there is little that would materially derail things, the firm added.
TD Cowen
Joseph Thome
Buy
maintain
$275 -> $300
2026-06-17
Reason
TD Cowen
Joseph Thome
Price Target
$275 -> $300
2026-06-17
maintain
Buy
Reason
TD Cowen analyst Joseph Thome raised the firm's price target on Axsome Therapeutics to $300 from $275 and keeps a Buy rating on the shares. The firm said management remains confident in Auvelity's growth potential following its recent discussion given the sales force expansion and the new Alzheimer's disease agitation indication. Cowen said its KOLs have been encouraged by the clinical data package of Auvelity across a wide range of patients with depression and believe it will continue to see adoption across the spectrum.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for AXSM
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Valuation Metrics

The current forward P/E ratio for Axsome Therapeutics Inc (AXSM.O) is 333.33, compared to its 5-year average forward P/E of 12.74. For a more detailed relative valuation and DCF analysis to assess Axsome Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
12.74
Current PE
333.33
Overvalued PE
123.49
Undervalued PE
-98.00

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-19.80
Current EV/EBITDA
-24.21
Overvalued EV/EBITDA
63.70
Undervalued EV/EBITDA
-103.31

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1197.76
Current PS
7.87
Overvalued PS
6847.17
Undervalued PS
-4451.64

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Whales Holding AXSM

E
Eventide Asset Management, LLC
Holding
AXSM
+33.34%
3M Return
P
Pallas Capital Advisors LLC
Holding
AXSM
+27.63%
3M Return
B
BVF Partners L.P.
Holding
AXSM
+23.36%
3M Return
N
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.
Holding
AXSM
+21.42%
3M Return
S
Sofinnova Investments, Inc.
Holding
AXSM
+19.29%
3M Return
V
Voleon Capital Management LP
Holding
AXSM
+11.46%
3M Return

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Frequently Asked Questions

What is Axsome Therapeutics Inc (AXSM) stock price today?

The current price of AXSM is 249.76 USD — it has increased 2.95

What is Axsome Therapeutics Inc (AXSM)'s business?

Axsome Therapeutics, Inc. is a fully integrated biopharmaceutical company. The Company focused on developing medicines for people impacted by central nervous system (CNS) conditions. Its commercial products include AUVELITY, SUNOSI, and SYMBRAVO. It is also advancing pipeline of novel product candidates in early- to late-stage development addressing a broad range of serious neurological and psychiatric conditions. Its product pipelines include AXS-05, AXS-12, and AXS-14. Its lead product candidate, AXS-05 (dextromethorphan-bupropion), is developed for the treatment of Alzheimer’s disease (AD) agitation and smoking cessation. Its AXS-12 (reboxetine) is a novel, oral, potent, highly selective investigational norepinephrine reuptake inhibitor (NRI) and cortical dopamine modulator being developed for the treatment of narcolepsy. Its AXS-14 (esreboxetine) is a novel, oral, potent, highly selective investigational NRI being developed for the management of fibromyalgia.

What is the price predicton of AXSM Stock?

Wall Street analysts forecast AXSM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for AXSM is209.54 USD with a low forecast of 153.00 USD and a high forecast of 260.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Axsome Therapeutics Inc (AXSM)'s revenue for the last quarter?

Axsome Therapeutics Inc revenue for the last quarter amounts to 191.20M USD, increased 57.42

What is Axsome Therapeutics Inc (AXSM)'s earnings per share (EPS) for the last quarter?

Axsome Therapeutics Inc. EPS for the last quarter amounts to -1.26 USD, increased 3.28

How many employees does Axsome Therapeutics Inc (AXSM). have?

Axsome Therapeutics Inc (AXSM) has 925 emplpoyees as of July 08 2026.

What is Axsome Therapeutics Inc (AXSM) market cap?

Today AXSM has the market capitalization of 12.85B USD.