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PRAX Overview

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0.000(0.000%)
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ET
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ET
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Intellectia

Loading chart...

High
327.610
Open
315.110
VWAP
319.52
Vol
609.13K
Mkt Cap
9.03B
Low
307.000
Amount
194.63M
EV/EBITDA(TTM)
--
Total Shares
27.88M
EV
7.95B
EV/OCF(TTM)
--
P/S(TTM)
--
Praxis Precision Medicines, Inc. is an integrated, central nervous system (CNS) precision neuroscience biopharmaceutical company, translating insights from genetic epilepsies into the development of therapies for CNS disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is a targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company's product candidates include Ulixacaltamide, Vormatrigine, Relutrigine, PRAX-080, Elsunersen, and others.
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Events Timeline

(ET)
2026-07-07
08:30:00
Praxis Collaborates with Remagine Labs to Develop Drug Patch
select
2026-06-22 (ET)
2026-06-22
08:30:00
Praxis Precision Receives FDA BTD for elsunersen
select
2026-06-02 (ET)
2026-06-02
12:10:00
Praxis Precision Shares Drop 15.4% to $283.47
select

News

stocktwits
7.0
07-01stocktwits
Tarsus Accused of Market Manipulation by Culper Research
  • Short Seller Allegations: Culper Research has accused Tarsus Pharmaceuticals of using questionable practices to boost sales of its sole product, XDEMVY, resulting in a 5% drop in stock price on Wednesday, potentially marking its worst day since April.
  • Medicare Copay Scheme: Culper claims Tarsus has funded copay assistance for Medicare patients through the HealthWell Foundation, with donations of $5.7 million in 2023 and an expected $31.2 million in 2024, arguing this violates the Anti-Kickback Statute and poses legal risks.
  • Inflated Market Size: Tarsus has touted a 25 million patient opportunity for Demodex blepharitis, but a survey indicates only 18% of patients are diagnosed, leading Culper to estimate a true market size closer to 5 million, with peak annual revenues for XDEMVY projected below $800 million.
  • Financial Guidance Downgrade: Culper asserts that Tarsus is likely to miss its 2026 guidance, as analysts have underestimated rising patient assistance and other SG&A costs, which could lead to further declines in stock price in the future.
NASDAQ.COM
9.0
06-30NASDAQ.COM
Praxis Drug Review Period Extended by Three Months
  • FDA Review Extension: The FDA has extended the review period for Praxis Precision Medicines' New Drug Application for Relutrigine by three months, moving the target action date from September 27, 2026, to December 27, 2026, due to significant amendments in clinical data sensitivity analyses submitted by the company.
  • No Safety Concerns: During the extension, the FDA did not identify any safety or manufacturing issues and did not request new clinical studies, indicating that the existing data is sufficient to continue the review process.
  • Positive Clinical Trial Results: In the Phase 2/3 EMBOLD trial, Relutrigine was generally well tolerated and demonstrated reductions in seizures along with behavioral and functional improvements, which further solidified the FDA's acceptance of the NDA for priority review.
  • Strong Market Performance: Praxis's stock has traded between $37.19 and $366.52 over the past year, closing at $350.56 on Monday with a 6.95% increase, reflecting investor confidence in the drug's future prospects.
seekingalpha
9.0
06-29seekingalpha
FDA Extends Review Period for Praxis Drug Application
  • Review Period Extended: The FDA has extended the review period for Praxis Precision Medicines' application for relutrigine by three months to December 27, due to the submission of additional sensitivity analyses, which the agency considers a 'major amendment.'
  • No New Studies Required: The extension does not require new studies from Praxis, nor were any safety or manufacturing issues mentioned, indicating the FDA's focus on existing data, which may facilitate a faster approval process.
  • Positive Market Reaction: Praxis's performance under FDA Breakthrough Therapy status has garnered market attention, particularly regarding its potential treatment for SCN2A and SCN8A developmental epileptic encephalopathies, which may boost investor confidence.
  • Optimistic Future Outlook: With other drugs like Ulixacaltamide expected to receive PDUFA in early 2027, Praxis demonstrates ongoing innovation and market potential in the neuroscience sector.
Newsfilter
9.0
06-29Newsfilter
FDA Extends Review Period for Praxis Drug Application
  • Review Period Extended: The FDA has extended the PDUFA date for Praxis Precision Medicines' relutrigine NDA from September 27, 2026, to December 27, 2026, allowing an additional three months for thorough review, indicating the FDA's significant attention to the drug.
  • Supplementary Data Analysis: This extension follows Praxis's submission of additional sensitivity analyses, which the FDA classified as a 'major amendment,' thereby enhancing the credibility of the application based on existing clinical data.
  • No New Clinical Studies Required: The FDA did not request new clinical studies nor raised any safety or manufacturing concerns, suggesting that the existing data is sufficient to support the review process, and Praxis remains confident in the market potential of relutrigine.
  • Urgent Patient Need: Praxis is actively preparing to deliver relutrigine to the patient community suffering from SCN2A and SCN8A developmental epileptic encephalopathies, emphasizing the drug's potential to address significant unmet medical needs.
NASDAQ.COM
9.0
06-22NASDAQ.COM
Praxis Receives FDA Breakthrough Therapy Designation for Elsunersen
  • FDA Breakthrough Designation: Praxis Precision Medicines' Elsunersen has received Breakthrough Therapy Designation from the U.S. FDA for treating seizures associated with SCN2A Developmental and Epileptic Encephalopathy, based on promising early clinical results, which is expected to expedite the therapy's development timeline.
  • Clinical Data Support: Findings from Part A of the EMBRAVE study indicate that patients treated with Elsunersen experienced a 77% reduction in monthly seizure frequency compared to the sham control group, with improvements sustained for up to one year in the open-label extension, demonstrating significant efficacy of the therapy.
  • Ongoing Registrational Study: Praxis is continuing enrollment in its EMBRAVE3 registrational trial, which follows a streamlined development pathway agreed upon with the FDA, planning to enroll approximately 30 patients, with all participants receiving Elsunersen for an initial 24-week treatment period followed by a 24-week extension.
  • Multiple Regulatory Designations: Elsunersen has received Breakthrough Therapy, Orphan Drug, and Rare Pediatric Disease Designations in the U.S., as well as Orphan Drug and PRIME status in Europe, reinforcing its potential to address a significant unmet medical need.
seekingalpha
9.0
06-22seekingalpha
Praxis Receives FDA Breakthrough Therapy Designation for Seizures
  • Breakthrough Therapy Designation: The US FDA has awarded Praxis Precision Medicines (PRAX) Breakthrough Therapy Designation for its seizure drug forelsunersen, marking a significant advancement in the treatment of SCN2A developmental and epileptic encephalopathy, which is expected to expedite the clinical development process.
  • Multiple Drug Status: The asset has already received Breakthrough Therapy, Orphan Drug, and Rare Pediatric Disease designations from the FDA, indicating its potential in treating rare diseases, which may attract more investor interest and enhance the company's market value.
  • Clinical Trial Progress: The pivotal study EMBRAVE3 is currently enrolling patients, demonstrating Praxis's proactive efforts in advancing the clinical trial of the drug, with successful completion potentially leading to significant commercial opportunities for the company.
  • Market Outlook Analysis: Praxis showcased its product line at recent healthcare conferences, and despite facing high market expectations for Essential Tremor, its stock price has declined due to setbacks in seizure therapy trials, reflecting a cautious market sentiment regarding its future prospects.
Wall Street analysts forecast PRAX stock price to rise
15 Analyst Rating
Wall Street analysts forecast PRAX stock price to rise
14 Buy
0 Hold
1 Sell
Strong Buy
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Needham
Ami Fadia
Buy
maintain
$510 -> $575
AI Analysis
2026-06-29
Reason
Needham
Ami Fadia
Price Target
$510 -> $575
AI Analysis
2026-06-29
maintain
Buy
Reason
Needham analyst Ami Fadia raised the firm's price target on Praxis Precision to $575 from $510 and keeps a Buy rating on the shares. The firm is incrementally more positive on Praxis after hosting an investor meeting with management, the analyst tells investors in a research note.
RBC Capital
Leonid Timashev
Outperform
initiated
$449
2026-06-17
Reason
RBC Capital
Leonid Timashev
Price Target
$449
2026-06-17
initiated
Outperform
Reason
RBC Capital analyst Leonid Timashev initiated coverage of Praxis Precision with an Outperform rating and $449 price target. The firm believes think ulixacaltamide has a "reasonable likelihood" of achieving over $4.3B in sales. RBC's regulatory checks suggest the essential tremor treatment can make it to market, and there is a "large unmet need and strong desire to prescribe" among physicians, the analyst tells investors in a research note. The firm sees a good entry point with the shares down 25% from recent highs.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PRAX
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Valuation Metrics

The current forward P/E ratio for Praxis Precision Medicines Inc (PRAX.O) is 0.00, compared to its 5-year average forward P/E of -3.91. For a more detailed relative valuation and DCF analysis to assess Praxis Precision Medicines Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.91
Current PE
0.00
Overvalued PE
-0.43
Undervalued PE
-7.39

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.35
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.02
Undervalued EV/EBITDA
-5.71

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
669.35
Current PS
25.76
Overvalued PS
2070.71
Undervalued PS
-732.01

Financials

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Whales Holding PRAX

L
Logos Global Management, L.P.
Holding
PRAX
+27.09%
3M Return
D
Driehaus Capital Management LLC
Holding
PRAX
+21.50%
3M Return
D
Deerfield Management Company, L.P.
Holding
PRAX
+19.41%
3M Return
S
Sofinnova Investments, Inc.
Holding
PRAX
+19.29%
3M Return
H
Hood River Capital Management LLC
Holding
PRAX
+19.09%
3M Return
C
Crestline Investors Inc.
Holding
PRAX
+16.60%
3M Return

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Frequently Asked Questions

What is Praxis Precision Medicines Inc (PRAX) stock price today?

The current price of PRAX is 323.95 USD — it has increased 3.33

What is Praxis Precision Medicines Inc (PRAX)'s business?

Praxis Precision Medicines, Inc. is an integrated, central nervous system (CNS) precision neuroscience biopharmaceutical company, translating insights from genetic epilepsies into the development of therapies for CNS disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is a targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company's product candidates include Ulixacaltamide, Vormatrigine, Relutrigine, PRAX-080, Elsunersen, and others.

What is the price predicton of PRAX Stock?

Wall Street analysts forecast PRAX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PRAX is456.71 USD with a low forecast of 95.00 USD and a high forecast of 843.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Praxis Precision Medicines Inc (PRAX)'s revenue for the last quarter?

Praxis Precision Medicines Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Praxis Precision Medicines Inc (PRAX)'s earnings per share (EPS) for the last quarter?

Praxis Precision Medicines Inc. EPS for the last quarter amounts to -3.20 USD, decreased -2.74

How many employees does Praxis Precision Medicines Inc (PRAX). have?

Praxis Precision Medicines Inc (PRAX) has 168 emplpoyees as of July 08 2026.

What is Praxis Precision Medicines Inc (PRAX) market cap?

Today PRAX has the market capitalization of 9.03B USD.