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ARWR Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
87.570
Open
87.275
VWAP
86.11
Vol
1.92M
Mkt Cap
12.25B
Low
83.790
Amount
164.90M
EV/EBITDA(TTM)
--
Total Shares
140.86M
EV
11.66B
EV/OCF(TTM)
--
P/S(TTM)
19.48
Arrowhead Pharmaceuticals, Inc. develops medicines that treat intractable diseases by silencing the genes that cause them. The Company's therapies, using a broad portfolio of ribonucleic acid (RNA) chemistries and modes of delivery, trigger the RNA interference (RNAi) mechanism to induce rapid, deep and durable knockdown of target genes. Its Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. It is focused on various therapeutic areas, such as cardiometabolic, pulmonary, liver, neuromuscular and others. It has over 18 discovered drug candidates in clinical trials ranging from early stage (Phase I) to late stage (Phase III). The Company's pipeline products include plozasiran, zodasiran, olpasiran, ARO-RAGE, SRP-1002, GSK4532990, fazirsiran, daplusiran/tomligisiran, ARO-CFB, ARO-INHBE, ARO-C3, ARO-PNPLA3, SRP-1001 (ARO-DUX4), SRP-1003 (ARO-DM1), SRP-1004 (ARO-ATXN2), and others.
Show More

Events Timeline

(ET)
2026-06-22
13:00:00
Arrowhead Pharmaceuticals Receives EC Approval for REDEMPLO to Reduce Triglycerides
select
2026-05-27 (ET)
2026-05-27
07:10:00
Arrowhead Pharmaceuticals Presents Interim Results of ARO-INHBE Clinical Trial
select
2026-05-26 (ET)
2026-05-26
10:20:00
Arrowhead Pharmaceuticals Presents Clinical Data for Plozasiran
select
2026-05-07 (ET)
2026-05-07
16:40:00
Arrowhead Pharmaceuticals Q2 Revenue $73.7M Beats Expectations
select
2026-05-05 (ET)
2026-05-05
08:10:00
Arrowhead Signs Exclusive License Agreement with Madrigal for ARO-PNPLA3
select
2026-05-01 (ET)
2026-05-01
07:40:00
Arrowhead Pharmaceuticals Receives Approval for Redemplo to Treat FCS
select
2026-04-24 (ET)
2026-04-24
06:50:00
Arrowhead Pharmaceuticals' REDEMPLO Receives Positive Opinion from EMA
select

News

stocktwits
9.0
06-25stocktwits
FDA Approves Tryngolza for Severe Hypertriglyceridemia Treatment
  • FDA Approval: The U.S. FDA approved Tryngolza on Wednesday as the first and only treatment to reduce triglycerides and the risk of acute pancreatitis in adults with severe hypertriglyceridemia, based on CORE and CORE2 trials showing up to 72% triglyceride reduction at six months.
  • Commercial Launch: Ionis plans to launch Tryngolza in the U.S. in July, administered as a once-monthly subcutaneous injection at doses of 50 mg or 80 mg, which is expected to significantly enhance treatment options for over three million Americans suffering from this condition.
  • Positive Stock Reaction: Following the FDA approval, Ionis Pharmaceuticals (IONS) shares rose 4% in after-hours trading, with Goldman Sachs raising its price target to $75, although this implies about a 2% downside from the current stock price, indicating optimistic market sentiment towards the new drug.
  • Analyst Ratings: According to Koyfin, 21 out of 24 analysts covering IONS rated it as 'Buy' or higher, with an average price target of $104.91, suggesting a potential upside of approximately 37% from Wednesday's closing price, reflecting strong confidence in Tryngolza's market potential.
Newsfilter
8.5
06-22Newsfilter
REDEMPLO Receives EU Approval for FCS Treatment
  • New Treatment Option: REDEMPLO (plozasiran) becomes the first siRNA medicine authorized by the EU for adult patients with familial chylomicronemia syndrome (FCS), providing a treatment option without the need for genetic confirmation, addressing a critical unmet need for these rare disease patients.
  • Clinical Data Support: The Phase 3 PALISADE study demonstrated that a 25 mg dose of REDEMPLO achieved an 80% reduction in triglyceride levels from baseline and an 83% reduction in the incidence of acute pancreatitis, showcasing its significant efficacy and long-term safety.
  • Significant Market Potential: With FCS patients typically having triglyceride levels exceeding 10 mmol/L (880 mg/dL), the launch of REDEMPLO not only offers new hope for patients but also has the potential to drive Arrowhead's expansion in global markets, enhancing its leadership in RNA interference therapies.
  • Accelerated Regulatory Progress: Arrowhead Pharmaceuticals plans to collaborate with relevant national authorities across the EU to swiftly bring REDEMPLO to market, reflecting its strong clinical data support and commitment to patient health, further solidifying its competitive edge in the RNAi therapeutic landscape.
Newsfilter
1.0
06-18Newsfilter
Arrowhead Pharmaceuticals Announces 2026 R&D Webinar Series
  • 2026 Summer Webinar Series: Arrowhead Pharmaceuticals plans to host a series of R&D webinars in 2026, focusing on multiple clinical-stage RNA interference medicines utilizing its proprietary TRiM™ platform, aimed at enhancing market awareness in RNA therapeutics.
  • Cardiometabolic Pipeline Focus: The first webinar is scheduled for June 29, 2026, concentrating on the cardiometabolic pipeline, featuring a keynote presentation by Dr. Steven Nissen from the Cleveland Clinic, showcasing Arrowhead's latest advancements in cardiovascular disease treatment.
  • Diverse Agenda: Each webinar will last 60 to 90 minutes, covering Arrowhead's technology and R&D processes, clinical candidates, and discussions on relevant disease areas, designed to attract the attention of investors and healthcare professionals.
  • Enhanced Market Engagement: Through these webinars, Arrowhead will provide live webcasts and replays, further enhancing interaction with investors and increasing the company's transparency and credibility in the biopharmaceutical industry.
Newsfilter
1.0
06-02Newsfilter
Arrowhead Pharmaceuticals to Participate in Upcoming Healthcare Conferences
  • Conference Participation: Arrowhead Pharmaceuticals is scheduled to participate in the 2026 Jefferies Global Healthcare Conference on June 3, 2026, at 8:10 AM EDT, showcasing its advancements in RNA interference, which is expected to attract investor interest and enhance the company's visibility.
  • Key Presentations: The company will also present at the Goldman Sachs 47th Annual Global Healthcare Conference on June 10, 2026, at 9:00 AM EDT, highlighting its RNAi therapeutic solutions for intractable diseases, potentially fostering communication and collaboration with prospective partners.
  • Platform Advantage: Arrowhead leverages its industry-leading TRiM™ platform to develop RNAi therapeutics that can precisely target various cell types, which is anticipated to enhance its competitiveness in clinical and commercial arenas while addressing significant unmet medical needs.
  • Investor Relations: Presentation materials and webcast links will be accessible via the investor section of the company's website, aiming to strengthen communication with investors, enhance transparency, and attract more investor attention.
Newsfilter
9.0
05-26Newsfilter
Arrowhead Pharmaceuticals Presents New Clinical Data for Plozasiran at EAS Congress
  • Clinical Data Support: Arrowhead Pharmaceuticals presented new clinical data for plozasiran at the 94th European Atherosclerosis Society Congress, indicating its use in patients with moderate-to-severe renal or moderate hepatic impairment without dose adjustment, highlighting the drug's importance in addressing patient needs.
  • Safety Assessment: Despite modest increases in plozasiran exposure among patients with moderate-to-severe renal or moderate hepatic impairment, pharmacodynamic responses (APOC3 and triglyceride reduction) were similar to control cohorts, indicating good safety and tolerability of the drug in these populations.
  • Pregnancy Impact: A case report suggests that preconception exposure to plozasiran may be associated with sustained lowering of triglyceride levels throughout pregnancy, providing new insights into the drug's application in special populations, although further data are needed to confirm its safety and efficacy.
  • Future Research Directions: Arrowhead plans to conduct additional trials to further evaluate the safety of plozasiran in patients with liver or renal disease, underscoring the company's commitment to developing innovative therapies for unmet medical needs.
PRnewswire
8.5
05-12PRnewswire
Cardiovascular Disease Costs Set to Skyrocket, Urgent Need for AI Solutions
  • Rising Cardiovascular Costs: The American Heart Association warns that U.S. heart disease costs are set to quadruple by 2050, with national healthcare spending nearing $5 trillion, compelling hospitals to rethink their diagnostic and treatment strategies for cardiac patients, thereby driving structural changes in the healthcare industry.
  • Rapid Growth of AI Cardiology Market: The global AI cardiology market is projected to grow from $2.78 billion this year to over $14 billion by 2034, reflecting a strong demand for innovative technologies as health systems rush to deploy machine learning tools to address diagnostic backlogs.
  • Showcasing VMS+™ 4.0 Technology: VentriPoint Diagnostics will showcase its AI-powered cardiac imaging platform at the AEPC conference in Italy, which converts standard 2D ultrasound scans into detailed 3D heart models, providing results comparable to cardiac MRI without the need for expensive machines and long wait times.
  • International Collaborations and Market Expansion: VentriPoint has established partnerships for regulatory approval of VMS+™ 4.0 in China and is promoting cardiac diagnostics in Costa Rica and Indigenous communities in Canada, demonstrating its potential for global market expansion and commercial momentum.
Wall Street analysts forecast ARWR stock price to rise
11 Analyst Rating
Wall Street analysts forecast ARWR stock price to rise
8 Buy
3 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
35.00
Averages
82.00
High
110.00
Current: 0.000
sliders
Low
35.00
Averages
82.00
High
110.00
Bernstein
Market Perform
maintain
$35 -> $46
AI Analysis
2026-05-13
Reason
Bernstein
Price Target
$35 -> $46
AI Analysis
2026-05-13
maintain
Market Perform
Reason
Bernstein raised the firm's price target on Arrowhead to $46 from $35 and keeps a Market Perform rating on the shares. Biotech has had a strong start to 2026, up 11% year-to-date, outperforming Pharma and the S&P. The firm's coverage is up 7% year-to-date on a simple-average basis, and down 3% cap weighted - smaller names have outperformed. Overall, Bernstein maintains a positive view on the sector, as it expects M&A and IPO activity to remain healthy, and it views recent changes to FDA leadership as a tailwind, particularly for less mature companies.
Chardan
Buy
maintain
$80 -> $90
2026-05-08
Reason
Chardan
Price Target
$80 -> $90
2026-05-08
maintain
Buy
Reason
Chardan raised the firm's price target on Arrowhead to $90 from $80 and keeps a Buy rating on the shares post the fiscal Q2 report. The U.S. launch of Redemplo is off to a good start, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ARWR
Unlock Now

Valuation Metrics

The current forward P/E ratio for Arrowhead Pharmaceuticals Inc (ARWR.O) is 97.09, compared to its 5-year average forward P/E of -3.54. For a more detailed relative valuation and DCF analysis to assess Arrowhead Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.54
Current PE
97.09
Overvalued PE
36.75
Undervalued PE
-43.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-11.76
Current EV/EBITDA
-21.47
Overvalued EV/EBITDA
21.78
Undervalued EV/EBITDA
-45.31

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
22.42
Current PS
36.00
Overvalued PS
33.85
Undervalued PS
11.00

Financials

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Whales Holding ARWR

S
Summit Partners Public Asset Management, LLC
Holding
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+37.64%
3M Return
S
Slate Path Capital LP
Holding
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+28.92%
3M Return
D
Driehaus Capital Management LLC
Holding
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+21.50%
3M Return
D
Deerfield Management Company, L.P.
Holding
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+19.41%
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Avoro Capital Advisors LLC
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+17.64%
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F
Fred Alger Management, LLC
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+16.98%
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Frequently Asked Questions

What is Arrowhead Pharmaceuticals Inc (ARWR) stock price today?

The current price of ARWR is 86.97 USD — it has increased 0.49

What is Arrowhead Pharmaceuticals Inc (ARWR)'s business?

Arrowhead Pharmaceuticals, Inc. develops medicines that treat intractable diseases by silencing the genes that cause them. The Company's therapies, using a broad portfolio of ribonucleic acid (RNA) chemistries and modes of delivery, trigger the RNA interference (RNAi) mechanism to induce rapid, deep and durable knockdown of target genes. Its Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. It is focused on various therapeutic areas, such as cardiometabolic, pulmonary, liver, neuromuscular and others. It has over 18 discovered drug candidates in clinical trials ranging from early stage (Phase I) to late stage (Phase III). The Company's pipeline products include plozasiran, zodasiran, olpasiran, ARO-RAGE, SRP-1002, GSK4532990, fazirsiran, daplusiran/tomligisiran, ARO-CFB, ARO-INHBE, ARO-C3, ARO-PNPLA3, SRP-1001 (ARO-DUX4), SRP-1003 (ARO-DM1), SRP-1004 (ARO-ATXN2), and others.

What is the price predicton of ARWR Stock?

Wall Street analysts forecast ARWR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ARWR is82.00 USD with a low forecast of 35.00 USD and a high forecast of 110.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Arrowhead Pharmaceuticals Inc (ARWR)'s revenue for the last quarter?

Arrowhead Pharmaceuticals Inc revenue for the last quarter amounts to 73.74M USD, decreased -86.41

What is Arrowhead Pharmaceuticals Inc (ARWR)'s earnings per share (EPS) for the last quarter?

Arrowhead Pharmaceuticals Inc. EPS for the last quarter amounts to -0.93 USD, decreased -133.82

How many employees does Arrowhead Pharmaceuticals Inc (ARWR). have?

Arrowhead Pharmaceuticals Inc (ARWR) has 711 emplpoyees as of July 08 2026.

What is Arrowhead Pharmaceuticals Inc (ARWR) market cap?

Today ARWR has the market capitalization of 12.25B USD.