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IRD Overview

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ET
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ET
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Intellectia

Loading chart...

High
4.170
Open
4.110
VWAP
4.01
Vol
1.03M
Mkt Cap
334.39M
Low
3.800
Amount
4.14M
EV/EBITDA(TTM)
--
Total Shares
82.57M
EV
302.02M
EV/OCF(TTM)
--
P/S(TTM)
25.60
Opus Genetics, Inc. is a clinical-stage ophthalmic biotechnology company. The Company is engaged in developing gene therapies for the treatment of inherited retinal diseases (IRDs) and other types of therapies for additional ophthalmic disorders. The Company’s pipeline includes adeno-associated virus (AAV)-based investigational gene therapies that address mutations in genes that cause different forms of bestrophinopathy, Leber congenital amaurosis (LCA) and retinitis pigmentosa. Its pipeline also includes OPGx-BEST1 investigational gene therapy, designed to address mutations in the BEST1 gene, which is associated with retinal degeneration. The pipeline also includes Phentolamine Ophthalmic Solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist being investigated to reduce pupil size, and APX3330, a novel small-molecule inhibitor of Ref-1 being investigated to slow the progression of non-proliferative diabetic retinopathy.
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Events Timeline

(ET)
2026-07-06
09:00:00
Nasdaq and S&P 500 Futures Rise as Chip Stocks Rebound
select
2026-07-06
07:30:00
Opus Genetics Aligns with FDA to Advance LCA5 Clinical Trial
select
2026-06-05 (ET)
2026-06-05
16:40:00
Company Not Selling 2.68M Shares of Common Stock
select

News

Newsfilter
8.5
07-06Newsfilter
PinnedOpus Genetics Aligns with FDA on Phase 3 Study for LCA5 Treatment
  • FDA Meeting Outcome: Opus Genetics confirmed the design of its Phase 3 clinical trial for LCA5-associated IRDs during a Type B RDEP meeting with the FDA, with dosing expected to begin in Q4 2026, marking a significant advancement in treating childhood blindness.
  • Trial Design Details: The study plans to enroll eight participants, utilizing microperimetry to assess treatment effects, with preliminary results from Phase 1/2 showing an average retinal sensitivity improvement of approximately 10.5 decibels, indicating potential efficacy of the treatment.
  • BLA Submission Prospects: The FDA indicated that Opus Genetics may submit a Biologics License Application (BLA) based on six-month efficacy data, paving the way for future market access and holding significant strategic importance for the company.
  • Therapeutic Potential: LCA5-associated inherited retinal disease represents a severe form of childhood blindness, and the FDA's ongoing support and engagement provide strong momentum for Opus Genetics' treatment program, expected to bring hope to patients and families.
NASDAQ.COM
9.0
07-06NASDAQ.COM
Opus Genetics Aligns with FDA on Phase 3 Trial Design
  • Trial Design Confirmation: Opus Genetics achieved alignment with the FDA during a Type B meeting, confirming the design of its Phase 3 clinical trial for LCA5-associated inherited retinal disease, marking a significant advancement in the rare disease sector.
  • Biologics License Application: The FDA indicated that Opus Genetics may submit a Biologics License Application based on efficacy at the six-month primary endpoint, with 12-month durability data to be submitted during the review process, signaling positive market potential for the product.
  • Participant Recruitment Progress: The Phase 3 study plans to enroll eight participants, with seven already enrolled and completing the run-in period, and dosing expected to begin in Q4 2026, demonstrating rapid clinical advancement by the company.
  • Positive Stock Reaction: In pre-market trading on NasdaqCM, Opus Genetics shares rose 2.55% to $4.3378, reflecting market optimism regarding the company's clinical progress.
Newsfilter
8.5
06-26Newsfilter
Opus Genetics Added to Russell Indexes, Enhancing Market Visibility
  • Inclusion in Russell Indexes: Opus Genetics will be added to the Russell 3000, 2000, and Microcap indexes effective June 29, 2026, marking a significant recognition of the company's progress in gene therapy, which is expected to enhance investor attention.
  • Market Capitalization Ranking: The Russell indexes include the top 4,000 U.S. stocks based on market capitalization as of April 30, 2026, and Opus's inclusion ensures automatic membership in both large-cap and small-cap indexes, further solidifying its market position.
  • Boost in Investor Confidence: CEO George Magrath stated that being part of the Russell indexes will provide greater visibility to investors, potentially facilitating future financing and partnership opportunities, thereby accelerating the clinical development of its gene therapy products.
  • Expanded Industry Influence: With approximately $12.2 trillion in assets benchmarked against the Russell indexes as of June 2025, Opus's inclusion will significantly enhance its influence in the biopharmaceutical sector, attracting more institutional investors to its innovative treatment solutions.
NASDAQ.COM
8.5
06-17NASDAQ.COM
Opus Genetics Updates on Gene Therapy Developments
  • Gene Therapy Progress: Opus Genetics provided updates on various gene therapies for inherited retinal diseases at the R&D Science Forum, with OPGx-RDH12 set to begin clinical testing in Q4 this year, targeting approximately 30,900 patients with LCA, indicating significant therapeutic potential.
  • Clinical Trial Plans: OPGx-MERTX, aimed at MERTK mutations causing severe vision loss, is expected to enter clinical testing in 2027, focusing on restoring retinal pigment epithelium metabolism, which suggests future treatment possibilities.
  • Vision Improvement Results: In the Phase 1/2 trial of OPGx-LCA5, significant vision improvements were observed in both adult and pediatric patients after 24 and 6 months respectively, demonstrating the therapy's effectiveness and durability.
  • Upcoming Trials: The company has initiated recruitment for the Phase 3 trial of OPGx-LCA5, with dosing expected to start in Q4 this year, while topline data from the Phase 1/2 trial for OPGx-BEST1 is anticipated in September 2026, further advancing the R&D pipeline.
CNBC
6.0
06-04CNBC
Wall Street's Latest Ratings and Price Target Adjustments
  • Broadcom Rating Adjustment: Morgan Stanley raised Broadcom's price target from $485 to $502, reflecting strong performance amid high expectations, indicating a sustained growth trend that may attract more investor interest.
  • RTX Upgraded to Buy: Jefferies upgraded RTX from hold to buy, emphasizing its leading position in aerospace and defense, with significant growth potential from market expansion and budget support, enhancing investor confidence.
  • FedEx Freight Coverage Initiated: Wolfe initiated coverage on FedEx Freight with an Outperform rating, expecting material EPS growth in the coming years driven by company-specific pricing and margin opportunities, indicating a positive market outlook.
  • Alphabet Maintained Buy Rating: Bank of America reiterated its buy rating on Alphabet, anticipating 2027 capex of $241 billion and $16 billion in free cash flow, showcasing strong performance in future market demand.
seekingalpha
9.5
05-12seekingalpha
Opus Genetics Reports Q1 Losses and Revenue Decline
  • Earnings Miss: Opus Genetics reported a Q1 GAAP EPS of -$0.75, missing expectations by $0.60, indicating significant challenges in profitability that could undermine investor confidence.
  • Revenue Decline: The company’s Q1 revenue of $2.16M represents a 50.6% year-over-year decline, falling short of expectations by $0.77M, reflecting weak market demand and poor product sales, which may lead to tighter cash flow in the future.
  • Financing Support: Opus Genetics secured up to $155M in financing from Oberland Capital, providing essential operational funds that will help the company maintain R&D and market expansion efforts amid adversity.
  • Historical Performance Review: Despite the poor Q1 results, historical earnings data suggests that the company has asymmetric upside potential with its LCA5 and BEST1 projects, indicating possible future business recovery.
Wall Street analysts forecast IRD stock price to rise
9 Analyst Rating
Wall Street analysts forecast IRD stock price to rise
9 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
6.00
Averages
8.00
High
9.00
Current: 0.000
sliders
Low
6.00
Averages
8.00
High
9.00
Chardan
Chardan
Buy
maintain
$13
AI Analysis
2026-07-06
New
Reason
Chardan
Chardan
Price Target
$13
AI Analysis
2026-07-06
New
maintain
Buy
Reason
After Opus Genetics announced that it has reached alignment with the FDA on the design of its registrational Phase 3 clinical trial evaluating OPGx-LCA5 for LCA5-associated IRD, an early-onset severe inherited retinal dystrophy, Chardan calls today's announcement a positive for OPGx-LCA5 as well as one that has an "encouraging read through" to the potential streamlined regulatory path for OPGx-BEST1 ahead of upcoming cohort 1 data in September. The firm has a Buy rating and $13 price target on Opus shares.
RBC Capital
Outperform
initiated
$10
2026-06-23
Reason
RBC Capital
Price Target
$10
2026-06-23
initiated
Outperform
Reason
RBC Capital initiated coverage of Opus Genetics with an Outperform rating and $10 price target. Opus is a gene therapy company focused on inherited retinal disease, notes the analyst, who thinks the setup is \"favorable\" given limited competition, de-risked science, and \"recent FDA leniency.\" While noting shares are up about 340% over the last year, the firm sees opportunity for additional upside with the upcoming BEST1 readout in September plus four clinical pipeline readouts in 2027.
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Valuation Metrics

The current forward P/E ratio for Opus Genetics Inc (IRD.O) is 12.00, compared to its 5-year average forward P/E of 0.33. For a more detailed relative valuation and DCF analysis to assess Opus Genetics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
0.33
Current PE
12.00
Overvalued PE
5.84
Undervalued PE
-5.18

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.27
Current EV/EBITDA
-3.19
Overvalued EV/EBITDA
0.95
Undervalued EV/EBITDA
-3.48

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
8.78
Current PS
23.55
Overvalued PS
16.09
Undervalued PS
1.48

Financials

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Whales Holding IRD

V
Voss Capital, LP
Holding
IRD
+26.67%
3M Return
K
KfW
Holding
IRD
+0.00%
3M Return

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Frequently Asked Questions

What is Opus Genetics Inc (IRD) stock price today?

The current price of IRD is 4.05 USD — it has decreased -0.49

What is Opus Genetics Inc (IRD)'s business?

Opus Genetics, Inc. is a clinical-stage ophthalmic biotechnology company. The Company is engaged in developing gene therapies for the treatment of inherited retinal diseases (IRDs) and other types of therapies for additional ophthalmic disorders. The Company’s pipeline includes adeno-associated virus (AAV)-based investigational gene therapies that address mutations in genes that cause different forms of bestrophinopathy, Leber congenital amaurosis (LCA) and retinitis pigmentosa. Its pipeline also includes OPGx-BEST1 investigational gene therapy, designed to address mutations in the BEST1 gene, which is associated with retinal degeneration. The pipeline also includes Phentolamine Ophthalmic Solution 0.75%, a non-selective alpha-1 and alpha-2 adrenergic antagonist being investigated to reduce pupil size, and APX3330, a novel small-molecule inhibitor of Ref-1 being investigated to slow the progression of non-proliferative diabetic retinopathy.

What is the price predicton of IRD Stock?

Wall Street analysts forecast IRD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for IRD is8.00 USD with a low forecast of 6.00 USD and a high forecast of 9.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Opus Genetics Inc (IRD)'s revenue for the last quarter?

Opus Genetics Inc revenue for the last quarter amounts to 2.16M USD, decreased -50.64

What is Opus Genetics Inc (IRD)'s earnings per share (EPS) for the last quarter?

Opus Genetics Inc. EPS for the last quarter amounts to -0.75 USD, increased 212.50

How many employees does Opus Genetics Inc (IRD). have?

Opus Genetics Inc (IRD) has 27 emplpoyees as of July 08 2026.

What is Opus Genetics Inc (IRD) market cap?

Today IRD has the market capitalization of 334.39M USD.